Basic Information:

  VIRBase ID:  

VHID00224041

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL148D:  MIMAT0001578          PPP1R11:  NM_021959     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL148D	PPP1R11
miRBase Accession/Entrez ID	MIMAT0001578	6992
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CFAP255//HCG-V//HCGV//IPP3//TCTE5//TCTEX5

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PPP1R11	chr6:30034903-30034904(+) m6A 5'UTR//intron       - chr6:30034962-30034963(+) m6A 5'UTR//intron       25456834//24981863 chr6:30035115-30035116(+) m6A 5'UTR//intron       24284625//25456834//24981863//27773535 chr6:30035217-30035218(+) m6A 5'UTR//CDS//intron       - chr6:30035229-30035230(+) m6A 5'UTR//CDS//intron       - chr6:30036333-30036334(+) m6A 5'UTR//intron       - chr6:30036370-30036371(+) m6A 5'UTR//CDS       - chr6:30036389-30036390(+) m6A 5'UTR//CDS       - chr6:30036426-30036427(+) m6A 5'UTR//CDS       - chr6:30036442-30036443(+) m6A 5'UTR//CDS       - chr6:30036449-30036450(+) m6A 5'UTR//CDS       - chr6:30036899-30036900(+) m6A CDS       - chr6:30037013-30037014(+) m6A CDS       24284625//24981863 chr6:30037833-30037834(+) m6A 3'UTR       - chr6:30037923-30037924(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL148D	Exosome K562 cells     24460325
	PPP1R11	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL148D	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL148D
Interactor2: PPP1R11

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg