Basic Information:

  VIRBase ID:  

VHID00223894

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL148D:  MIMAT0001578          PITX1:  NM_002653     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL148D	PITX1
miRBase Accession/Entrez ID	MIMAT0001578	5307
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BFT//CCF//LBNBG//POTX//PTX1

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PITX1	chr5:134363498-134363499(-) m6A 3'UTR       24284625 chr5:134363634-134363635(-) m6A 3'UTR       24284625//27773536 chr5:134363715-134363716(-) m6A 3'UTR       24284625//27773536 chr5:134363966-134363967(-) m6A 3'UTR       24284625//24209618//24981863//27371828//27773536//22575960//22608085 chr5:134363996-134363997(-) m6A 3'UTR       24284625//24209618//24981863//27371828//27773536//22575960//22608085 chr5:134364016-134364017(-) m6A 3'UTR       24284625//24209618//24981863//27371828//27773536//22575960//22608085 chr5:134364037-134364038(-) m6A 3'UTR       24284625//24209618//24981863//27371828//27773536//22575960//22608085 chr5:134364264-134364265(-) m6A 3'UTR       24284625//24209618//24981863//27773535//27371828//27773536//22575960//22608085 chr5:134364287-134364288(-) m6A 3'UTR       24284625//24209618//24981863//27773535//27371828//27773536//22575960//22608085 chr5:134364355-134364356(-) m6A 3'UTR       24284625//24209618//24981863//27773535//27371828//27773536//22575960//22608085 chr5:134364543-134364544(-) m6A CDS       24284625//24209618//24981863//27371828//22575960 chr5:134364586-134364587(-) m6A CDS       24284625//24209618//24981863//27371828//22575960 chr5:134364949-134364950(-) Y CDS       26075521 chr5:134364952-134364953(-) m6A CDS       24284625//24209618//24981863//27371828//27773536//22575960//22608085 chr5:134364997-134364998(-) m6A CDS//exon       24284625//24209618//24981863//27371828//27773536//22575960//22608085 chr5:134366991-134366992(-) m6A CDS//exon       24284625//24209618//24981863//27371828//27773536//22575960//22608085 chr5:134367035-134367036(-) m6A CDS//exon       24284625//24209618//24981863//27371828//27773536//22575960//22608085 chr5:134367108-134367109(-) m1A CDS//exon       26863410 chr5:134367161-134367162(-) m6A CDS//exon       24284625//24209618//24981863//27371828//27773536//22575960//22608085 chr5:134367178-134367179(-) m6A CDS//exon       24284625//24209618//24981863//27371828//27773536//22575960//22608085 chr5:134367293-134367294(-) m6A exon//intron       24284625//27371828//27773536 chr5:134367319-134367320(-) m6A exon//intron       24284625 chr5:134367332-134367333(-) m6A exon//intron       24284625 chr5:134367383-134367384(-) m6A exon//intron       24284625 chr5:134367499-134367500(-) m6A exon//intron       24284625 chr5:134367523-134367524(-) m6A exon//intron       24284625 chr5:134367531-134367532(-) m6A exon//intron       24284625 chr5:134367551-134367552(-) m6A exon//intron       24284625 chr5:134367567-134367568(-) m6A exon//intron       24284625 chr5:134369437-134369438(-) m6A CDS       27371828//27773536 chr5:134369533-134369534(-) Y CDS       26075521 chr5:134369880-134369881(-) m6A 5'UTR//intron       24981863 chr5:134369914-134369915(-) m6A 5'UTR//intron       24981863 chr5:134369942-134369943(-) m6A 5'UTR//intron       24981863 chr5:134369951-134369952(-) m6A 5'UTR//intron       24981863 chr5:134370195-134370196(-) m6A 5'UTR//intron       24209618//24981863 chr5:134370237-134370238(-) m6A 5'UTR//intron       24284625 chr5:134370278-134370279(-) m6A 5'UTR//intron       24284625 chr5:134370317-134370318(-) m6A 5'UTR//intron       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL148D	Exosome K562 cells     24460325
	PITX1	Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL148D	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL148D
Interactor2: PITX1

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg