Basic Information:

  VIRBase ID:  

VHID00223874

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL148D:  MIMAT0001578          PBX2:  NM_002586     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL148D	PBX2
miRBase Accession/Entrez ID	MIMAT0001578	5089
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	G17//HOX12//PBX2MHC

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PBX2	chr6:32152696-32152697(-) m6A 3'UTR       27773535 chr6:32152717-32152718(-) m6A 3'UTR       27773535 chr6:32152742-32152743(-) m6A 3'UTR       27773535 chr6:32153458-32153459(-) m6A 3'UTR       24981863//27773535//22608085 chr6:32153488-32153489(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr6:32153590-32153591(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr6:32153667-32153668(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr6:32153674-32153675(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr6:32153687-32153688(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr6:32153867-32153868(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr6:32153880-32153881(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr6:32153898-32153899(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr6:32154019-32154020(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr6:32154058-32154059(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr6:32154086-32154087(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085 chr6:32154191-32154192(-) m6A CDS//exon       24284625//24209618//25456834//27773535//27371828 chr6:32154337-32154338(-) m6A exon//intron       24284625 chr6:32154521-32154522(-) m6A exon//intron       - chr6:32154819-32154820(-) m6A exon//intron       24284625 chr6:32155084-32155085(-) m6A CDS//exon       27773535 chr6:32155101-32155102(-) m6A CDS//exon       27773535 chr6:32155128-32155129(-) m6A CDS//exon       27773535 chr6:32155218-32155219(-) m6A exon//intron       27773535 chr6:32155272-32155273(-) m6A exon//intron       27773535 chr6:32156084-32156085(-) m6A CDS//exon       27773536 chr6:32156097-32156098(-) m6A CDS//exon       27773536 chr6:32156105-32156106(-) m6A CDS//exon       27773536 chr6:32156220-32156221(-) m6A CDS//exon       27773535//27773536 chr6:32156241-32156242(-) m6A CDS//exon       27773535//27773536 chr6:32156337-32156338(-) m6A exon//intron       27773535//27773536 chr6:32156365-32156366(-) m6A exon//intron       27773535//27773536 chr6:32156379-32156380(-) m6A exon//intron       27773535//27773536 chr6:32156391-32156392(-) m6A exon//intron       27773535 chr6:32156457-32156458(-) m6A exon//intron       27773535 chr6:32156462-32156463(-) m6A exon//intron       27773535 chr6:32156502-32156503(-) m6A CDS//exon       27773535 chr6:32156558-32156559(-) m6A CDS//exon       24284625//27773535//27371828 chr6:32156569-32156570(-) m6A CDS//exon       24284625//27773535//27371828 chr6:32156663-32156664(-) m6A exon//intron       24284625//27773535//27371828 chr6:32156719-32156720(-) m6A exon//intron       27773535 chr6:32156826-32156827(-) m6A exon//intron       24284625//24981863//27773535//27371828 chr6:32157528-32157529(-) m6A CDS//exon       24284625//25456834//24981863//28052920//27773535//27371828//27773536 chr6:32157537-32157538(-) m6A CDS//exon       24284625//25456834//24981863//28052920//27773535//27371828//27773536 chr6:32157585-32157586(-) m6A CDS//exon       24284625//25456834//24981863//28052920//27773535//27371828//27773536 chr6:32157834-32157835(-) m6A 5'UTR       24284625//25456834//24981863//27371828//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL148D	Exosome K562 cells     24460325
	PBX2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HeLa-S3 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL148D	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL148D
Interactor2: PBX2

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg