Basic Information:

  VIRBase ID:  

VHID00223812

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL148D:  MIMAT0001578          MMP14:  NM_004995     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL148D	MMP14
miRBase Accession/Entrez ID	MIMAT0001578	4323
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	MMP-14//MMP-X1//MT-MMP//MT-MMP 1//MT1-MMP//MT1MMP//MTMMP1//WNCHRS

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MMP14	chr14:23309288(+) A-I      intronic chr14:23309385(+) A-I      intronic chr14:23309373(+) A-I      intronic chr14:23309450(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MMP14	chr14:23305790-23305791(+) m6A 5'UTR//exon       24209618//25456834//24981863 chr14:23305795-23305796(+) m6A 5'UTR//exon       24209618//25456834//24981863 chr14:23305832-23305833(+) m6A 5'UTR//exon       24209618//25456834//24981863//27773535 chr14:23305855-23305856(+) m6A 5'UTR//exon       24209618//25456834//24981863//27773535 chr14:23305871-23305872(+) m6A 5'UTR//exon       24209618//25456834//24981863//27773535 chr14:23305933-23305934(+) m6A 5'UTR//exon       24209618//25456834//24981863 chr14:23306023-23306024(+) m6A 5'UTR//exon       25456834 chr14:23306043-23306044(+) m6A CDS//exon       25456834 chr14:23306400-23306401(+) m6A CDS//intron       25456834 chr14:23306418-23306419(+) m6A CDS//intron       25456834 chr14:23306463-23306464(+) m6A CDS//intron       - chr14:23313966-23313967(+) m6A CDS//exon       - chr14:23313985-23313986(+) m6A CDS//exon       - chr14:23314512-23314513(+) m6A CDS//exon       - chr14:23314940-23314941(+) m6A CDS//intron       24209618//25456834//24981863//27773535 chr14:23314980-23314981(+) m6A CDS//intron       24209618//25456834//24981863//27773535 chr14:23315009-23315010(+) m6A CDS//intron       24209618//25456834//24981863//27773535//27371828 chr14:23315050-23315051(+) m6A CDS//intron       24209618//25456834//24981863//27371828 chr14:23315197-23315198(+) m6A CDS//intron       24209618//25456834//24981863 chr14:23315237-23315238(+) m6A CDS//intron       24209618//25456834//24981863 chr14:23315283-23315284(+) m6A 3'UTR//intron       24209618//25456834//24981863 chr14:23315506-23315507(+) m6A 3'UTR//intron       24209618 chr14:23315572-23315573(+) m6A 3'UTR//intron       24209618 chr14:23315580-23315581(+) m6A 3'UTR//intron       24209618 chr14:23315811-23315812(+) m6A 3'UTR//intron       25456834 chr14:23315825-23315826(+) m6A 3'UTR//intron       25456834 chr14:23315899-23315900(+) m6A 3'UTR//intron       24209618//25456834 chr14:23315930-23315931(+) m6A 3'UTR//intron       24209618//25456834 chr14:23315948-23315949(+) m6A 3'UTR//intron       24209618//25456834 chr14:23316016-23316017(+) m6A 3'UTR//intron       24209618//25456834//24981863 chr14:23316106-23316107(+) m6A 3'UTR//intron       24209618//25456834//24981863//27773535//27371828 chr14:23316117-23316118(+) m6A 3'UTR//intron       24209618//25456834//24981863//27773535//27371828 chr14:23316151-23316152(+) m6A 3'UTR//intron       24209618//25456834//24981863//27773535//27371828 chr14:23316174-23316175(+) m6A 3'UTR//intron       24209618//25456834//24981863//27773535//27371828 chr14:23316626-23316627(+) m6A 3'UTR//intron       24209618 chr14:23316641-23316642(+) m6A 3'UTR//intron       24209618

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL148D	Exosome K562 cells     24460325
	MMP14	Cytosol HeLa-S3 cells     - Exosome Blood     - Nucleus K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL148D	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL148D
Interactor2: MMP14

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg