Basic Information:

  VIRBase ID:  

VHID00223788

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL148D:  MIMAT0001578          MAT2A:  NM_005911     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL148D	MAT2A
miRBase Accession/Entrez ID	MIMAT0001578	4144
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	MATA2//MATII//SAMS2

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MAT2A	chr2:85766418-85766419(+) m6A CDS//exon       24284625//22575960 chr2:85768471-85768472(+) m6A CDS//exon       27773535 chr2:85768558-85768559(+) m6A exon//intron       27773535 chr2:85769579-85769580(+) m6A exon//intron       27773535 chr2:85769724-85769725(+) m6A CDS//exon       22575960 chr2:85770826-85770827(+) m6A CDS       24284625//24981863//22608085 chr2:85770854-85770855(+) m6A CDS       24284625//24981863//22608085 chr2:85770918-85770919(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr2:85771057-85771058(+) m6A 3'UTR       24284625//24981863//22608085 chr2:85771518-85771519(+) m6A 3'UTR       27773535 chr2:85771633-85771634(+) m6A 3'UTR       24284625//24981863//22608085 chr2:85771666-85771667(+) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085 chr2:85771693-85771694(+) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085 chr2:85771869-85771870(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr2:85771892-85771893(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr2:85771915-85771916(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr2:85772145-85772146(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr2:85772157-85772158(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL148D	Exosome K562 cells     24460325
	MAT2A	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL148D	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL148D
Interactor2: MAT2A

Evidence Support:

Prediction-Evidence	miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg