Basic Information:

  VIRBase ID:  

VHID00223778

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL148D:  MIMAT0001578          LTBR:  NM_002342     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL148D	LTBR
miRBase Accession/Entrez ID	MIMAT0001578	4055
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	D12S370//LT-BETA-R//TNF-R-III//TNFCR//TNFR-RP//TNFR2-RP//TNFR3//TNFRSF3

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	LTBR	chr12:6484553-6484554(+) m6A exon       25456834//24981863 chr12:6484613-6484614(+) m6A 5'UTR//exon//intron       25456834//24981863 chr12:6484619-6484620(+) m6A 5'UTR//exon//intron       25456834//24981863 chr12:6484652-6484653(+) m6A 5'UTR//exon//intron       25456834//24981863 chr12:6493775-6493776(+) m6A 5'UTR//CDS//exon       24284625 chr12:6493780-6493781(+) m6A 5'UTR//CDS//exon       24284625 chr12:6493790-6493791(+) m6A 5'UTR//CDS//exon       24284625 chr12:6494223-6494224(+) m6A 5'UTR//CDS//exon       24284625 chr12:6494271-6494272(+) m6A 5'UTR//CDS//exon       24284625 chr12:6494436-6494437(+) m6A CDS//exon       24284625 chr12:6494708-6494709(+) m6A exon//intron       24284625 chr12:6494715-6494716(+) m6A exon//intron       24284625 chr12:6494721-6494722(+) m6A exon//intron       24284625 chr12:6494734-6494735(+) m6A exon//intron       24284625 chr12:6495520-6495521(+) m6A CDS//exon       24284625 chr12:6495617-6495618(+) m6A exon//intron       24284625 chr12:6495631-6495632(+) m6A exon//intron       24284625 chr12:6495698-6495699(+) m6A exon//intron       24284625 chr12:6497666-6497667(+) m6A 3'UTR//CDS//exon//intron       24284625 chr12:6498056-6498057(+) m6A exon//intron       24284625 chr12:6498367-6498368(+) m1A exon//intron       26863196 chr12:6499106-6499107(+) m6A exon//intron       27773535 chr12:6499452-6499453(+) m6A CDS//exon       24284625 chr12:6499477-6499478(+) m6A CDS//exon       24284625 chr12:6499892-6499893(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22575960 chr12:6499907-6499908(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22575960 chr12:6499924-6499925(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22575960 chr12:6499943-6499944(+) m6A CDS//exon       24284625//24209618//24981863//26404942//22575960 chr12:6499972-6499973(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960 chr12:6500037-6500038(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960 chr12:6500080-6500081(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960 chr12:6500120-6500121(+) Cm 3'UTR//exon       - chr12:6500235-6500236(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960 chr12:6500285-6500286(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960 chr12:6500307-6500308(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960 chr12:6500326-6500327(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960 chr12:6500365-6500366(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960 chr12:6500506-6500507(+) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22575960 chr12:6500534-6500535(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22575960 chr12:6500544-6500545(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22575960 chr12:6500727-6500728(+) m6A 3'UTR//exon       24284625//24981863//27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL148D	Exosome K562 cells     24460325
	LTBR	Chromatin K562 cells     - Cytosol K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL148D	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL148D
Interactor2: LTBR

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg