Basic Information:

  VIRBase ID:  

VHID00223721

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL148D:  MIMAT0001578          IL11:  NM_000641     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL148D	IL11
miRBase Accession/Entrez ID	MIMAT0001578	3589
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	AGIF//IL-11

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	IL11	chr19:55880537(-) A-I      intronic chr19:55880487(-) A-I      intronic chr19:55880501(-) A-I      intronic chr19:55876050(-) A-I      3'UTR chr19:55876126(-) A-I      3'UTR chr19:55876451(-) A-I      3'UTR chr19:55876606(-) A-I      3'UTR

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	IL11	chr19:55876215-55876216(-) m6A 3'UTR       24981863 chr19:55876953-55876954(-) m6A 3'UTR       24981863 chr19:55876960-55876961(-) m6A 3'UTR       24981863 chr19:55877147-55877148(-) m6A 3'UTR       24209618 chr19:55877173-55877174(-) m6A 3'UTR       24209618 chr19:55881697-55881698(-) m6A 5'UTR       24981863 chr19:55881745-55881746(-) m6A 5'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL148D	Exosome K562 cells     24460325
	IL11	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL148D	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL148D
Interactor2: IL11

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg