Basic Information:

  VIRBase ID:  

VHID00223662

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL148D:  MIMAT0001578          GRM4:  NM_001282847     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL148D	GRM4
miRBase Accession/Entrez ID	MIMAT0001578	2914
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	GPRC1D//mGlu4//MGLUR4

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	GRM4	chr6:34054951(-) A-I      intronic chr6:34077989(-) A-I      intronic chr6:34009943(-) A-I      intronic chr6:34086916(-) A-I      intronic chr6:34081021(-) A-I      intronic chr6:34055030(-) A-I      intronic chr6:34055013(-) A-I      intronic chr6:34081053(-) A-I      intronic chr6:34055946(-) A-I      intronic chr6:34077988(-) A-I      intronic chr6:34080989(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	GRM4	chr6:34029989(-) A-I intron -    15342557 chr6:34030024(-) A-I intron -    15342557 chr6:34030029(-) A-I intron -    15342557 chr6:34030095(-) A-I intron -    15342557 chr6:34030145(-) A-I intron -    15342557 chr6:34030168(-) A-I intron -    15342557 chr6:34030731(-) A-I intron -    15342557 chr6:34101332(-) A-I exon 5'UTR    19478186

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	GRM4	chr6:33990332-33990333(-) m6A 3'UTR//exon       25456834//24981863//27371828 chr6:33990355-33990356(-) m6A 3'UTR//exon       25456834//24981863//27371828 chr6:33990368-33990369(-) m6A 3'UTR//exon       25456834//24981863//27371828 chr6:33990423-33990424(-) m6A 3'UTR//exon       25456834//24981863//27371828 chr6:33992181-33992182(-) m6A exon//intron       25456834 chr6:33992206-33992207(-) m6A exon//intron       25456834 chr6:33992237-33992238(-) m6A exon//intron       25456834 chr6:33992256-33992257(-) m6A exon//intron       25456834 chr6:34003637-34003638(-) m6A 3'UTR//CDS//exon       25456834 chr6:34003686-34003687(-) m6A 3'UTR//CDS//exon       25456834 chr6:34003694-34003695(-) m6A 3'UTR//CDS//exon       25456834 chr6:34003703-34003704(-) m6A 3'UTR//CDS//exon       25456834 chr6:34003724-34003725(-) m6A 3'UTR//CDS//exon       25456834 chr6:34003866-34003867(-) m6A 3'UTR//CDS//exon       25456834//24981863//22575960 chr6:34003906-34003907(-) m6A 3'UTR//CDS//exon       25456834//24981863//27371828//22575960 chr6:34004014-34004015(-) m6A 3'UTR//CDS//exon       25456834//22575960 chr6:34004180-34004181(-) m6A 3'UTR//CDS//exon       25456834//24981863//27371828//22575960 chr6:34004228-34004229(-) m6A 3'UTR//CDS//exon       25456834//24981863//27371828//22575960 chr6:34004292-34004293(-) m6A 3'UTR//CDS//exon       25456834 chr6:34100938-34100939(-) m6A CDS//exon//intron       25456834 chr6:34100953-34100954(-) m6A CDS//exon//intron       25456834 chr6:34100992-34100993(-) m6A CDS//exon//intron       25456834 chr6:34101066-34101067(-) m6A CDS//exon//intron       25456834//24981863 chr6:34101130-34101131(-) m6A CDS//exon//intron       25456834//24981863 chr6:34101466-34101467(-) m6A 5'UTR//exon//intron       25456834//24981863//27371828//27773536 chr6:34101522-34101523(-) m6A 5'UTR//exon//intron       25456834//24981863//27371828 chr6:34101540-34101541(-) m6A 5'UTR//intron       25456834//24981863//27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL148D	Exosome K562 cells     24460325
	GRM4	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL148D	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL148D
Interactor2: GRM4

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg