Basic Information:

  VIRBase ID:  

VHID00223465

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL148D:  MIMAT0001578          CD28:  NM_006139     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL148D	CD28
miRBase Accession/Entrez ID	MIMAT0001578	940
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	Tp44

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CD28	chr2:204600611(+) A-I      3'UTR chr2:204600571(+) A-I      3'UTR chr2:204576821(+) A-I      intronic chr2:204592740(+) A-I      intronic chr2:204573698(+) A-I      intronic chr2:204576653(+) A-I      intronic chr2:204600575(+) A-I      3'UTR chr2:204600610(+) A-I      3'UTR chr2:204600685(+) A-I      3'UTR chr2:204600569(+) A-I      3'UTR chr2:204600652(+) A-I      3'UTR chr2:204581585(+) A-I      intronic chr2:204571801(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CD28	chr2:204571801(+) A-G intron -    22484847 chr2:204581585(+) A-G intron -    22484847 chr2:204589316(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CD28	chr2:204591476-204591477(+) m6A CDS//intron       26404942 chr2:204599803-204599804(+) m6A 3'UTR       26404942 chr2:204599917-204599918(+) m6A 3'UTR       26404942 chr2:204600000-204600001(+) m6A 3'UTR       26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL148D	Exosome K562 cells     24460325
	CD28	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hcmv-miR-UL148D	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL148D
Interactor2: CD28

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg