Basic Information:

  VIRBase ID:  

VHID00221097

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL36-5p:  MIMAT0001576          ERAP1:  NM_001349244     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL36-5p	ERAP1
miRBase Accession/Entrez ID	MIMAT0001576	51752
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	A-LAP//ALAP//APPILS//ARTS-1//ARTS1//ERAAP//ERAAP1//PILS-AP//PILSAP

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ERAP1	chr5:96105534(-) A-I      intronic chr5:96108385(-) A-I      intronic chr5:96123193(-) A-I      intronic chr5:96108400(-) A-I      intronic chr5:96108401(-) A-I      intronic chr5:96108418(-) A-I      intronic chr5:96108422(-) A-I      intronic chr5:96108435(-) A-I      intronic chr5:96123170(-) A-I      intronic chr5:96123185(-) A-I      intronic chr5:96108384(-) A-I      intronic chr5:96105470(-) A-I      intronic chr5:96105472(-) A-I      intronic chr5:96105473(-) A-I      intronic chr5:96105475(-) A-I      intronic chr5:96105478(-) A-I      intronic chr5:96105486(-) A-I      intronic chr5:96105494(-) A-I      intronic chr5:96105499(-) A-I      intronic chr5:96105504(-) A-I      intronic chr5:96105533(-) A-I      intronic chr5:96134412(-) A-I      intronic chr5:96137303(-) A-I      intronic chr5:96133114(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ERAP1	chr5:96110490(-) A-I exon 3'UTR    22327324 chr5:96119944(-) T-C intron -    22484847 chr5:96119957(-) T-C intron -    22484847 chr5:96120043(-) T-C intron -    22484847 chr5:96120048(-) T-C intron -    22484847 chr5:96120049(-) T-C intron -    22484847 chr5:96133177(-) T-C intron -    22484847 chr5:96133178(-) T-C intron -    22484847 chr5:96110544(-) A-G exon 3'UTR    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ERAP1	chr5:96098108-96098109(-) m6A 3'UTR       27773535 chr5:96111643-96111644(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085 chr5:96111693-96111694(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr5:96111708-96111709(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr5:96111715-96111716(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr5:96111737-96111738(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr5:96111762-96111763(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22608085 chr5:96111791-96111792(-) m6A 3'UTR//intron       24284625//24981863//27773535 chr5:96127801-96127802(-) Cm CDS//exon       - chr5:96139157-96139158(-) m6A 5'UTR//CDS       24284625//27773535 chr5:96139257-96139258(-) m6A 5'UTR//CDS       24284625//27773535 chr5:96139275-96139276(-) m6A 5'UTR//CDS       24284625//24209618//24981863//27773535 chr5:96139394-96139395(-) m6A 5'UTR//CDS       24284625//24209618//24981863//27773535 chr5:96139420-96139421(-) m6A 5'UTR//CDS       24284625//24209618//24981863//27773535 chr5:96139496-96139497(-) m6A 5'UTR//CDS       24284625//24209618//24981863//28052920//27773535//22608085 chr5:96140529-96140530(-) m6A 5'UTR//intron       24284625//24209618//24981863//27371828 chr5:96143568-96143569(-) m6A 5'UTR       24981863//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hcmv-miR-UL36-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	ERAP1	Chromatin K562 cells     - Cytosol HeLa-S3 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL36-5p
Interactor2: ERAP1

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg