Basic Information:

  VIRBase ID:  

VHID00220445

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL22A-3p:  MIMAT0001575          PACRGL:  NR_133933     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL22A-3p	PACRGL
miRBase Accession/Entrez ID	MIMAT0001575	133015
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C4orf28

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PACRGL	chr4:20711390(+) A-I      Syn:Leu->Leu chr4:20718091(+) A-I      intronic chr4:20718086(+) A-I      intronic chr4:20708262(+) A-I      intronic chr4:20710642(+) A-I      intronic chr4:20708338(+) A-I      intronic chr4:20708404(+) A-I      intronic chr4:20729484(+) A-I      3'UTR chr4:20729479(+) A-I      3'UTR chr4:20710658(+) A-I      intronic chr4:20710682(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PACRGL	chr4:20702227-20702228(+) m6A 5'UTR//exon//intron       - chr4:20702302-20702303(+) m6A 5'UTR//exon//intron       - chr4:20706144-20706145(+) m6A CDS       24981863 chr4:20706299-20706300(+) m6A CDS       24981863 chr4:20706322-20706323(+) m6A CDS       24981863 chr4:20706388-20706389(+) m6A CDS       24981863 chr4:20706400-20706401(+) m6A CDS       24981863 chr4:20754322-20754323(+) m6A 3'UTR       25456834//24981863//27773535//22608085 chr4:20754417-20754418(+) m6A 3'UTR       25456834//24981863//27773535//22608085 chr4:20754442-20754443(+) m6A 3'UTR       25456834//24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PACRGL	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL22A-3p
Interactor2: PACRGL

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg