Basic Information:

  VIRBase ID:  

VHID00220205

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL22A-3p:  MIMAT0001575          POLR1B:  NM_019014     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL22A-3p	POLR1B
miRBase Accession/Entrez ID	MIMAT0001575	84172
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	A135//RPA135//RPA2//Rpo1-2//TCS4

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	POLR1B	chr2:113318492(+) A-I      intronic chr2:113318487(+) A-I      intronic chr2:113318490(+) A-I      intronic chr2:113311026(+) A-I      ncRNA chr2:113311047(+) A-I      ncRNA chr2:113311077(+) A-I      ncRNA chr2:113311091(+) A-I      ncRNA chr2:113318491(+) A-I      intronic chr2:113310990(+) A-I      ncRNA chr2:113306233(+) A-I      intronic chr2:113311002(+) A-I      ncRNA chr2:113311007(+) A-I      ncRNA chr2:113311019(+) A-I      ncRNA chr2:113334372(+) A-I      3'UTR chr2:113317301(+) A-I      intronic chr2:113317325(+) A-I      intronic chr2:113317337(+) A-I      intronic chr2:113317349(+) A-I      intronic chr2:113321415(+) A-I      intronic chr2:113312597(+) A-I      intronic chr2:113331455(+) A-I      intronic chr2:113330950(+) A-I      intronic chr2:113321450(+) A-I      intronic chr2:113321423(+) A-I      intronic chr2:113318387(+) A-I      intronic chr2:113332081(+) A-I      intronic chr2:113331479(+) A-I      intronic chr2:113313204(+) A-I      intronic chr2:113319434(+) A-I      intronic chr2:113318567(+) A-I      intronic chr2:113314764(+) A-I      intronic chr2:113315174(+) A-I      intronic chr2:113331674(+) A-I      intronic chr2:113332095(+) A-I      intronic chr2:113312596(+) A-I      intronic chr2:113301427(+) A-I      intronic chr2:113301595(+) A-I      intronic chr2:113301856(+) A-I      intronic chr2:113303321(+) A-I      intronic chr2:113311733(+) A-I      intronic chr2:113311957(+) A-I      intronic chr2:113311984(+) A-I      intronic chr2:113312362(+) A-I      intronic chr2:113318539(+) A-I      intronic chr2:113312363(+) A-I      intronic chr2:113314752(+) A-I      intronic chr2:113321211(+) A-I      intronic chr2:113332066(+) A-I      intronic chr2:113318495(+) A-I      intronic chr2:113312963(+) A-I      intronic chr2:113332162(+) A-I      intronic chr2:113314605(+) A-I      intronic chr2:113321429(+) A-I      intronic chr2:113319454(+) A-I      intronic chr2:113317481(+) A-I      intronic chr2:113318379(+) A-I      intronic chr2:113305508(+) A-I      intronic chr2:113314622(+) A-I      intronic chr2:113318396(+) A-I      intronic chr2:113332048(+) A-I      intronic chr2:113316335(+) A-I      intronic chr2:113303286(+) A-I      intronic chr2:113311843(+) A-I      intronic chr2:113312598(+) A-I      intronic chr2:113318527(+) A-I      intronic chr2:113311849(+) A-I      intronic chr2:113334373(+) A-I      3'UTR chr2:113334414(+) A-I      3'UTR chr2:113334265(+) A-I      3'UTR chr2:113334406(+) A-I      3'UTR chr2:113315280(+) A-I      intronic chr2:113303296(+) A-I      intronic chr2:113332220(+) A-I      intronic chr2:113319458(+) A-I      intronic chr2:113313136(+) A-I      intronic chr2:113314736(+) A-I      intronic chr2:113316227(+) A-I      intronic chr2:113313135(+) A-I      intronic chr2:113312643(+) A-I      intronic chr2:113313122(+) A-I      intronic chr2:113312860(+) A-I      intronic chr2:113301555(+) A-I      intronic chr2:113318448(+) A-I      intronic chr2:113321284(+) A-I      intronic chr2:113301479(+) A-I      intronic chr2:113315239(+) A-I      intronic chr2:113320515(+) A-I      intronic chr2:113318531(+) A-I      intronic chr2:113313154(+) A-I      intronic chr2:113315177(+) A-I      intronic chr2:113331690(+) A-I      intronic chr2:113319484(+) A-I      intronic chr2:113315254(+) A-I      intronic chr2:113332147(+) A-I      intronic chr2:113314756(+) A-I      intronic chr2:113312678(+) A-I      intronic chr2:113318447(+) A-I      intronic chr2:113314677(+) A-I      intronic chr2:113321293(+) A-I      intronic chr2:113315279(+) A-I      intronic chr2:113320432(+) A-I      intronic chr2:113316066(+) A-I      intronic chr2:113313003(+) A-I      intronic chr2:113303268(+) A-I      intronic chr2:113312599(+) A-I      intronic chr2:113311153(+) A-I      ncRNA chr2:113311159(+) A-I      ncRNA

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	POLR1B	chr2:113334241(+) A-I intron -    22327324 chr2:113334241(+) A-G intron -    21725310   //22484847 chr2:113301479(+) A-G intron -    22484847 chr2:113303268(+) A-G intron -    22484847 chr2:113310983(+) A-G intron -    22484847 chr2:113311843(+) A-G intron -    22484847 chr2:113311849(+) A-G intron -    22484847 chr2:113311978(+) A-G intron -    22484847 chr2:113313135(+) A-G intron -    22484847 chr2:113313136(+) A-G intron -    22484847 chr2:113314605(+) A-G intron -    22484847 chr2:113314606(+) A-G intron -    22484847 chr2:113314622(+) A-G intron -    22484847 chr2:113314631(+) A-G intron -    22484847 chr2:113314669(+) A-G intron -    22484847 chr2:113314677(+) A-G intron -    22484847 chr2:113315175(+) A-G intron -    22484847 chr2:113315177(+) A-G intron -    22484847 chr2:113315254(+) A-G intron -    22484847 chr2:113316066(+) A-G intron -    22484847 chr2:113316289(+) A-G intron -    22484847 chr2:113316335(+) A-G intron -    22484847 chr2:113318378(+) A-G intron -    22484847 chr2:113318379(+) A-G intron -    22484847 chr2:113318396(+) A-G intron -    22484847 chr2:113318447(+) A-G intron -    22484847 chr2:113318448(+) A-G intron -    22484847 chr2:113318463(+) A-G intron -    22484847 chr2:113318495(+) A-G intron -    22484847 chr2:113318527(+) A-G intron -    22484847 chr2:113318535(+) A-G intron -    22484847 chr2:113319437(+) T-C intron -    22484847 chr2:113319449(+) A-G intron -    22484847 chr2:113319458(+) A-G intron -    22484847 chr2:113321284(+) A-G intron -    22484847 chr2:113321289(+) A-G intron -    22484847 chr2:113321293(+) A-G intron -    22484847 chr2:113321429(+) A-G intron -    22484847 chr2:113321461(+) A-G intron -    22484847 chr2:113332028(+) A-G intron -    22484847 chr2:113334414(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	POLR1B	chr2:113299654-113299655(+) m6A 5'UTR       24981863 chr2:113299661-113299662(+) m6A 5'UTR       24981863 chr2:113299675-113299676(+) m6A 5'UTR//intron       25456834//24981863 chr2:113299695-113299696(+) m6A 5'UTR//intron       25456834//24981863 chr2:113299857-113299858(+) m6A 5'UTR//intron       25456834//22608085 chr2:113299915-113299916(+) m6A 5'UTR//intron       25456834//22608085 chr2:113299921-113299922(+) m6A 5'UTR//intron       25456834//22608085 chr2:113299955-113299956(+) m6A 5'UTR//intron       25456834//24981863//22608085 chr2:113299986-113299987(+) m6A 5'UTR//CDS       25456834//24981863//22608085 chr2:113300019-113300020(+) m6A 5'UTR//CDS       25456834//24981863//22608085 chr2:113300044-113300045(+) m6A 5'UTR//CDS       25456834//24981863//22608085 chr2:113300096-113300097(+) m6A 5'UTR//CDS       25456834//24981863//22608085 chr2:113300157-113300158(+) m6A 5'UTR//CDS       25456834//24981863 chr2:113330209-113330210(+) m6A 3'UTR//CDS//intron       26404942 chr2:113330232-113330233(+) m6A 3'UTR//CDS       26404942 chr2:113331224-113331225(+) m6A 3'UTR//CDS       24981863 chr2:113331257-113331258(+) m6A 3'UTR//CDS       24209618//24981863 chr2:113331320-113331321(+) m6A 3'UTR//CDS       24209618//24981863//22608085 chr2:113332524-113332525(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:113332599-113332600(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr2:113332632-113332633(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr2:113332764-113332765(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr2:113332858-113332859(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:113332869-113332870(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:113332920-113332921(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:113332937-113332938(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:113332953-113332954(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:113333263-113333264(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:113333277-113333278(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:113333290-113333291(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr2:113333334-113333335(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr2:113333419-113333420(+) m6A 3'UTR       24209618//24981863//22608085 chr2:113333432-113333433(+) m6A 3'UTR       24209618//24981863//22608085 chr2:113333440-113333441(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr2:113333657-113333658(+) m6A 3'UTR       24284625//22608085 chr2:113333728-113333729(+) m6A 3'UTR       22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	POLR1B	Chromatin HCC cell line (HepG2)|K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus HCC cell line (HepG2)|K562 cells     - Nucleoplasm HCC cell line (HepG2)|K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL22A-3p
Interactor2: POLR1B

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg