Basic Information:

  VIRBase ID:  

VHID00219769

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL22A-3p:  MIMAT0001575          NAT10:  NM_024662     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL22A-3p	NAT10
miRBase Accession/Entrez ID	MIMAT0001575	55226
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ALP//Kre33//NET43

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NAT10	chr11:34149821(+) A-I      intronic chr11:34149842(+) A-I      intronic chr11:34149826(+) A-I      intronic chr11:34128610(+) A-I      intronic chr11:34149820(+) A-I      intronic chr11:34155590(+) A-I      intronic chr11:34128661(+) A-I      intronic chr11:34157729(+) A-I      intronic chr11:34149846(+) A-I      intronic chr11:34129213(+) A-I      intronic chr11:34147295(+) A-I      intronic chr11:34151418(+) A-I      intronic chr11:34149780(+) A-I      intronic chr11:34155600(+) A-I      intronic chr11:34151219(+) A-I      intronic chr11:34128784(+) A-I      intronic chr11:34147300(+) A-I      intronic chr11:34128698(+) A-I      intronic chr11:34129405(+) A-I      intronic chr11:34155596(+) A-I      intronic chr11:34129301(+) A-I      intronic chr11:34143169(+) A-I      intronic chr11:34128798(+) A-I      intronic chr11:34129250(+) A-I      intronic chr11:34128829(+) A-I      intronic chr11:34129350(+) A-I      intronic chr11:34157359(+) A-I      intronic chr11:34129219(+) A-I      intronic chr11:34129342(+) A-I      intronic chr11:34143616(+) A-I      intronic chr11:34147470(+) A-I      intronic chr11:34129264(+) A-I      intronic chr11:34143602(+) A-I      intronic chr11:34147255(+) A-I      intronic chr11:34143153(+) A-I      intronic chr11:34128680(+) A-I      intronic chr11:34129347(+) A-I      intronic chr11:34129403(+) A-I      intronic chr11:34157363(+) A-I      intronic chr11:34129311(+) A-I      intronic chr11:34129328(+) A-I      intronic chr11:34157771(+) A-I      intronic chr11:34153505(+) A-I      intronic chr11:34157812(+) A-I      intronic chr11:34138167(+) A-I      intronic chr11:34149722(+) A-I      intronic chr11:34128817(+) A-I      intronic chr11:34157648(+) A-I      intronic chr11:34128681(+) A-I      intronic chr11:34157358(+) A-I      intronic chr11:34140323(+) A-I      intronic chr11:34149648(+) A-I      intronic chr11:34157685(+) A-I      intronic chr11:34128671(+) A-I      intronic chr11:34129354(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NAT10	chr11:34128680(+) A-I intron -    22327324 chr11:34128680(+) A-G intron -    22484847 chr11:34128681(+) A-G intron -    22484847 chr11:34129219(+) A-G intron -    22484847 chr11:34129342(+) A-G intron -    22484847 chr11:34129347(+) A-G intron -    22484847 chr11:34129354(+) A-G intron -    22484847 chr11:34129403(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NAT10	chr11:34127226-34127227(+) m6A 5'UTR//exon       24284625//24981863//22575960 chr11:34135341-34135342(+) Y CDS       26075521 chr11:34139120-34139121(+) Cm intron       - chr11:34145928-34145929(+) m6A CDS//intron       - chr11:34145938-34145939(+) m6A CDS//intron       - chr11:34149050-34149051(+) m6A CDS//intron       - chr11:34152456-34152457(+) m6A CDS//intron       - chr11:34163346-34163347(+) m6A CDS//intron       24209618//24981863//27773535 chr11:34163850-34163851(+) m6A CDS//exon//intron       24209618//24981863//27773535 chr11:34163885-34163886(+) m6A CDS//exon//intron       24284625//24209618//24981863//27773535 chr11:34165035-34165036(+) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr11:34167657-34167658(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr11:34167663-34167664(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr11:34167669-34167670(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr11:34167689-34167690(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:34167697-34167698(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:34167704-34167705(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:34167720-34167721(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:34167748-34167749(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:34167795-34167796(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:34167810-34167811(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:34167936-34167937(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr11:34168168-34168169(+) m6A 3'UTR       24284625//24981863 chr11:34168190-34168191(+) m6A 3'UTR       24284625 chr11:34168285-34168286(+) m6A 3'UTR//exon       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	NAT10	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Insoluble cytoplasm K562 cells     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL22A-3p
Interactor2: NAT10

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg