Basic Information:

  VIRBase ID:  

VHID00218155

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL22A-5p:  MIMAT0001574          C1orf174:  NM_207356     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL22A-5p	C1orf174
miRBase Accession/Entrez ID	MIMAT0001574	339448
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	C1orf174	chr1:3815032(-) A-I      intronic chr1:3814417(-) A-I      intronic chr1:3814325(-) A-I      intronic chr1:3814405(-) A-I      intronic chr1:3814428(-) A-I      intronic chr1:3814499(-) A-I      intronic chr1:3814902(-) A-I      intronic chr1:3814891(-) A-I      intronic chr1:3807837(-) A-I      ncRNA chr1:3814296(-) A-I      intronic chr1:3814392(-) A-I      intronic chr1:3815058(-) A-I      intronic chr1:3814813(-) A-I      intronic chr1:3814831(-) A-I      intronic chr1:3814952(-) A-I      intronic chr1:3810409(-) A-I      intronic chr1:3815066(-) A-I      intronic chr1:3806093(-) A-I      3'UTR chr1:3814500(-) A-I      intronic chr1:3814989(-) A-I      intronic chr1:3814366(-) A-I      intronic chr1:3814819(-) A-I      intronic chr1:3814522(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	C1orf174	chr1:3806177(-) A-I exon 3'UTR    21960545 chr1:3814296(-) A-G intron -    22484847 chr1:3814366(-) A-G intron -    22484847 chr1:3814392(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	C1orf174	chr1:3806255-3806256(-) m6A 3'UTR//exon       24981863//27773535 chr1:3806331-3806332(-) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr1:3806337-3806338(-) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr1:3806343-3806344(-) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr1:3806405-3806406(-) m6A 3'UTR//exon       24284625//24981863//26404942//27773535//22608085 chr1:3806413-3806414(-) m6A 3'UTR//exon       24284625//24981863//26404942//27773535//22608085 chr1:3807211-3807212(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085 chr1:3807245-3807246(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr1:3807321-3807322(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085 chr1:3807347-3807348(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085 chr1:3807482-3807483(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085 chr1:3807558-3807559(-) m6A CDS//exon       27773535 chr1:3807595-3807596(-) m6A CDS//exon       27773535 chr1:3809272-3809273(-) m6A exon//intron       - chr1:3809321-3809322(-) m6A exon//intron       - chr1:3809457-3809458(-) m6A CDS//exon       27773536 chr1:3812169-3812170(-) m6A exon//intron       27371828 chr1:3812218-3812219(-) m6A exon//intron       27371828 chr1:3812279-3812280(-) m6A exon//intron       25456834//27371828 chr1:3812332-3812333(-) m6A exon//intron       - chr1:3816819-3816820(-) m6A 5'UTR//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	C1orf174	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL22A-5p
Interactor2: C1orf174

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg