Basic Information:

  VIRBase ID:  

VHID00217545

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL22A-5p:  MIMAT0001574          PCGF3:  NM_001317836     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL22A-5p	PCGF3
miRBase Accession/Entrez ID	MIMAT0001574	10336
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	DONG1//RNF3//RNF3A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PCGF3	chr4:705311(+) A-I      intronic chr4:729276(+) A-I      intronic chr4:705326(+) A-I      intronic chr4:705327(+) A-I      intronic chr4:705376(+) A-I      intronic chr4:705386(+) A-I      intronic chr4:729212(+) A-I      intronic chr4:729228(+) A-I      intronic chr4:729174(+) A-I      intronic chr4:705607(+) A-I      intronic chr4:705747(+) A-I      intronic chr4:733106(+) A-I      intronic chr4:757830(+) A-I      intronic chr4:722873(+) A-I      intronic chr4:729126(+) A-I      intronic chr4:747051(+) A-I      intronic chr4:747337(+) A-I      intronic chr4:729121(+) A-I      intronic chr4:747386(+) A-I      intronic chr4:742226(+) A-I      intronic chr4:733074(+) A-I      intronic chr4:705310(+) A-I      intronic chr4:732427(+) A-I      intronic chr4:742049(+) A-I      intronic chr4:742171(+) A-I      intronic chr4:732549(+) A-I      intronic chr4:750065(+) A-I      intronic chr4:732383(+) A-I      intronic chr4:733189(+) A-I      intronic chr4:735406(+) A-I      intronic chr4:747025(+) A-I      intronic chr4:732536(+) A-I      intronic chr4:735195(+) A-I      intronic chr4:733101(+) A-I      intronic chr4:747036(+) A-I      intronic chr4:729078(+) A-I      intronic chr4:747188(+) A-I      intronic chr4:730059(+) A-I      intronic chr4:733114(+) A-I      intronic chr4:733153(+) A-I      intronic chr4:751901(+) A-I      intronic chr4:747625(+) A-I      intronic chr4:747187(+) A-I      intronic chr4:735397(+) A-I      intronic chr4:747350(+) A-I      intronic chr4:747351(+) A-I      intronic chr4:751835(+) A-I      intronic chr4:747035(+) A-I      intronic chr4:742248(+) A-I      intronic chr4:750201(+) A-I      intronic chr4:750064(+) A-I      intronic chr4:735256(+) A-I      intronic chr4:733075(+) A-I      intronic chr4:730105(+) A-I      intronic chr4:705679(+) A-I      intronic chr4:751820(+) A-I      intronic chr4:751701(+) A-I      intronic chr4:747110(+) A-I      intronic chr4:747480(+) A-I      intronic chr4:747352(+) A-I      intronic chr4:705671(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PCGF3	chr4:732553(+) A-G intron -    22484847 chr4:733101(+) A-G intron -    22484847 chr4:733114(+) A-G intron -    22484847 chr4:746995(+) A-G intron -    22484847 chr4:747014(+) T-C intron -    22484847 chr4:747025(+) A-G intron -    22484847 chr4:747036(+) A-G intron -    22484847 chr4:747041(+) A-G intron -    22484847 chr4:747110(+) A-G intron -    22484847 chr4:747699(+) T-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PCGF3	chr4:699641-699642(+) m6A 5'UTR//exon       24981863 chr4:699678-699679(+) m6A 5'UTR//exon       24981863 chr4:699717-699718(+) m6A 5'UTR//exon       24981863 chr4:699752-699753(+) m6A 5'UTR//exon       24981863 chr4:724437-724438(+) m6A 5'UTR//exon       24284625 chr4:724878-724879(+) m6A 5'UTR//exon       24284625//24209618 chr4:726223-726224(+) m6A 5'UTR//intron       - chr4:727497-727498(+) m6A 5'UTR//CDS//exon       - chr4:727694-727695(+) m6A 5'UTR//CDS//intron       24981863//22608085 chr4:727700-727701(+) m6A 5'UTR//CDS//intron       24981863//22608085 chr4:727994-727995(+) m6A 3'UTR//5'UTR//intron       24981863 chr4:728012-728013(+) m6A 3'UTR//5'UTR//intron       24981863 chr4:737318-737319(+) m6A 3'UTR//CDS       24284625//24209618//24981863 chr4:737332-737333(+) m6A 3'UTR//CDS       24284625//24209618//24981863 chr4:737346-737347(+) m6A 3'UTR//CDS       24284625//24209618//24981863 chr4:737664-737665(+) m6A exon//intron       24284625//24209618//24981863 chr4:737674-737675(+) m6A exon//intron       24284625//24209618//24981863 chr4:738392-738393(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863 chr4:738414-738415(+) m6A 3'UTR//CDS//exon       24209618//24981863 chr4:738447-738448(+) m6A 3'UTR//CDS//exon       24209618 chr4:755098-755099(+) m6A 3'UTR//CDS//exon       24209618 chr4:755179-755180(+) m6A 3'UTR//CDS       24284625//24209618//24981863 chr4:758775-758776(+) m6A 3'UTR//CDS       24284625//24209618//24981863 chr4:758808-758809(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085 chr4:759845-759846(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr4:759856-759857(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr4:759890-759891(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr4:759936-759937(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr4:759960-759961(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr4:759965-759966(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr4:760023-760024(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr4:760056-760057(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr4:760267-760268(+) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr4:760389-760390(+) m6A 3'UTR//intron       24284625//25456834//24981863//27773535//22608085 chr4:760452-760453(+) m6A 3'UTR//intron       25456834//24981863//27773535//22608085 chr4:760508-760509(+) m6A 3'UTR       25456834//24981863//27773535//22608085 chr4:760519-760520(+) m6A 3'UTR       25456834//24981863//27773535//22608085 chr4:760607-760608(+) m6A 3'UTR       25456834//24981863 chr4:760827-760828(+) m6A 3'UTR       24284625//25456834//27773535//27371828 chr4:760937-760938(+) m6A 3'UTR       27773535 chr4:761087-761088(+) m6A 3'UTR       27773535//22608085 chr4:761121-761122(+) m6A 3'UTR       27773535//22608085 chr4:761247-761248(+) m6A 3'UTR       27773535//22608085 chr4:761396-761397(+) m6A 3'UTR       - chr4:761725-761726(+) m6A 3'UTR       24284625 chr4:762000-762001(+) m6A 3'UTR       24284625//27773535 chr4:762046-762047(+) m6A 3'UTR       24284625//25456834//27773535 chr4:762063-762064(+) m6A 3'UTR       24284625//25456834//27773535 chr4:762276-762277(+) m6A 3'UTR       27773535 chr4:762326-762327(+) m6A 3'UTR       27773535 chr4:762416-762417(+) m6A 3'UTR       24981863//27773535 chr4:762479-762480(+) m6A 3'UTR       24981863//27773535 chr4:762707-762708(+) m6A 3'UTR       27773535 chr4:762757-762758(+) m6A 3'UTR       27773535 chr4:762928-762929(+) m6A 3'UTR       24284625//27371828//27773536 chr4:762980-762981(+) m6A 3'UTR       24284625//27371828//27773536 chr4:763371-763372(+) m6A 3'UTR       27773535 chr4:763595-763596(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PCGF3	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL22A-5p
Interactor2: PCGF3

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg