Basic Information:

  VIRBase ID:  

VHID00217195

  Virus:  

Human betaherpesvirus 5 (HHV-5)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-UL22A-5p:  MIMAT0001574          CLCN6:  NR_046428     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-UL22A-5p	CLCN6
miRBase Accession/Entrez ID	MIMAT0001574	1185
Organism	Human betaherpesvirus 5 (HHV-5)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CLC-6//CONRIBA

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CLCN6	chr1:11868940(+) A-I      intronic chr1:11882385(+) A-I      intronic chr1:11902754(+) A-I      3'UTR chr1:11882383(+) A-I      intronic chr1:11882379(+) A-I      intronic chr1:11882367(+) A-I      intronic chr1:11868985(+) A-I      intronic chr1:11868972(+) A-I      intronic chr1:11868946(+) A-I      intronic chr1:11882415(+) A-I      intronic chr1:11875592(+) A-I      intronic chr1:11871605(+) A-I      intronic chr1:11875546(+) A-I      intronic chr1:11875582(+) A-I      intronic chr1:11881538(+) A-I      intronic chr1:11868386(+) A-I      intronic chr1:11871565(+) A-I      intronic chr1:11869535(+) A-I      intronic chr1:11868971(+) A-I      intronic chr1:11870865(+) A-I      intronic chr1:11869565(+) A-I      intronic chr1:11871193(+) A-I      intronic chr1:11871496(+) A-I      intronic chr1:11880646(+) A-I      3'UTR chr1:11870894(+) A-I      intronic chr1:11870890(+) A-I      intronic chr1:11871701(+) A-I      intronic chr1:11883337(+) A-I      intronic chr1:11880645(+) A-I      3'UTR chr1:11871540(+) A-I      intronic chr1:11880601(+) A-I      3'UTR chr1:11882534(+) A-I      intronic chr1:11882528(+) A-I      intronic chr1:11880569(+) A-I      3'UTR chr1:11881522(+) A-I      intronic chr1:11872064(+) A-I      intronic chr1:11869529(+) A-I      intronic chr1:11870921(+) A-I      intronic chr1:11871566(+) A-I      intronic chr1:11871678(+) A-I      intronic chr1:11880745(+) A-I      3'UTR chr1:11881534(+) A-I      intronic chr1:11882562(+) A-I      intronic chr1:11869533(+) A-I      intronic chr1:11874835(+) A-I      intronic chr1:11873724(+) A-I      intronic chr1:11883459(+) A-I      intronic chr1:11871171(+) A-I      intronic chr1:11880730(+) A-I      3'UTR chr1:11869012(+) A-I      intronic chr1:11882535(+) A-I      intronic chr1:11867945(+) A-I      intronic chr1:11882552(+) A-I      intronic chr1:11874567(+) A-I      intronic chr1:11880703(+) A-I      3'UTR chr1:11883440(+) A-I      intronic chr1:11870031(+) A-I      intronic chr1:11882347(+) A-I      intronic chr1:11870094(+) A-I      intronic chr1:11870873(+) A-I      intronic chr1:11882416(+) A-I      intronic chr1:11874505(+) A-I      intronic chr1:11881085(+) A-I      intronic chr1:11874969(+) A-I      intronic chr1:11882500(+) A-I      intronic chr1:11881053(+) A-I      intronic chr1:11870908(+) A-I      intronic chr1:11880744(+) A-I      3'UTR chr1:11882409(+) A-I      intronic chr1:11874436(+) A-I      intronic chr1:11867857(+) A-I      intronic chr1:11874446(+) A-I      intronic chr1:11874579(+) A-I      intronic chr1:11883546(+) A-I      intronic chr1:11871557(+) A-I      intronic chr1:11871161(+) A-I      intronic chr1:11883455(+) A-I      intronic chr1:11882445(+) A-I      intronic chr1:11871123(+) A-I      intronic chr1:11873631(+) A-I      intronic chr1:11873171(+) A-I      intronic chr1:11871027(+) A-I      intronic chr1:11881054(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CLCN6	chr1:11867945(+) A-G intron -    22484847 chr1:11869012(+) A-G intron -    22484847 chr1:11869529(+) A-G intron -    22484847 chr1:11869533(+) A-G intron -    22484847 chr1:11870873(+) A-G intron -    22484847 chr1:11871027(+) A-G intron -    22484847 chr1:11871557(+) A-G intron -    22484847 chr1:11871566(+) A-G intron -    22484847 chr1:11874436(+) A-G intron -    22484847 chr1:11874505(+) A-G intron -    22484847 chr1:11874969(+) A-G intron -    22484847 chr1:11880703(+) A-G intron -    22484847 chr1:11880730(+) A-G intron -    22484847 chr1:11881054(+) A-G intron -    22484847 chr1:11882347(+) A-G intron -    22484847 chr1:11882409(+) A-G intron -    22484847 chr1:11882416(+) A-G intron -    22484847 chr1:11882535(+) A-G intron -    22484847 chr1:11882552(+) A-G intron -    22484847 chr1:11882562(+) A-G intron -    22484847 chr1:11883440(+) A-G intron -    22484847 chr1:11883455(+) A-G intron -    22484847 chr1:11885815(+) G-A intron -    22484847 chr1:11870031(+) A-G intron -    22484847 chr1:11870094(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CLCN6	chr1:11866385-11866386(+) m6A CDS//exon       24284625//25456834//24981863 chr1:11867202-11867203(+) m6A CDS//exon       24284625//25456834//24981863 chr1:11867239-11867240(+) m6A CDS//exon       25456834 chr1:11894559-11894560(+) m6A CDS       - chr1:11896145-11896146(+) m6A CDS       - chr1:11897137-11897138(+) m6A CDS       - chr1:11900648-11900649(+) m6A 3'UTR       24981863 chr1:11900679-11900680(+) m6A 3'UTR       24981863 chr1:11902405-11902406(+) m6A 3'UTR       24284625 chr1:11902436-11902437(+) m6A 3'UTR       24284625//24981863 chr1:11902512-11902513(+) m6A 3'UTR       24284625//24981863 chr1:11902579-11902580(+) m6A 3'UTR       24981863 chr1:11902778-11902779(+) m6A 3'UTR       - chr1:11902842-11902843(+) m6A 3'UTR       24284625//25456834 chr1:11902853-11902854(+) m6A 3'UTR       24284625//25456834 chr1:11902994-11902995(+) m6A 3'UTR       25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CLCN6	Chromatin K562 cells     - Cytosol HeLa-S3 cells|K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-UL22A-5p
Interactor2: CLCN6

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg