Basic Information:

  VIRBase ID:  

VHID00206888

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H5:  MIMAT0015650          PNPLA3:  NM_025225     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H5	PNPLA3
miRBase Accession/Entrez ID	MIMAT0015650	80339
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ADPN//C22orf20//iPLA(2)epsilon

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PNPLA3	chr22:44339877(+) A-I      intronic chr22:44339826(+) A-I      intronic chr22:44339808(+) A-I      intronic chr22:44336609(+) A-I      intronic chr22:44336585(+) A-I      intronic chr22:44336550(+) A-I      intronic chr22:44339786(+) A-I      intronic chr22:44330076(+) A-I      intronic chr22:44339795(+) A-I      intronic chr22:44339755(+) A-I      intronic chr22:44339738(+) A-I      intronic chr22:44338700(+) A-I      intronic chr22:44336809(+) A-I      intronic chr22:44329463(+) A-I      intronic chr22:44329367(+) A-I      intronic chr22:44327541(+) A-I      intronic chr22:44327538(+) A-I      intronic chr22:44336638(+) A-I      intronic chr22:44327530(+) A-I      intronic chr22:44327525(+) A-I      intronic chr22:44325078(+) A-I      intronic chr22:44339852(+) A-I      intronic chr22:44343077(+) A-I      3'UTR chr22:44343078(+) A-I      3'UTR chr22:44343079(+) A-I      3'UTR chr22:44330177(+) A-I      intronic chr22:44330176(+) A-I      intronic chr22:44329488(+) A-I      intronic chr22:44326896(+) A-I      intronic chr22:44326886(+) A-I      intronic chr22:44326818(+) A-I      intronic chr22:44325338(+) A-I      intronic chr22:44325235(+) A-I      intronic chr22:44323284(+) A-I      intronic chr22:44339928(+) A-I      intronic chr22:44339834(+) A-I      intronic chr22:44330179(+) A-I      intronic chr22:44343100(+) A-I      3'UTR chr22:44343145(+) A-I      3'UTR chr22:44343043(+) A-I      3'UTR chr22:44343038(+) A-I      3'UTR chr22:44343087(+) A-I      3'UTR chr22:44343086(+) A-I      3'UTR chr22:44343057(+) A-I      3'UTR chr22:44343053(+) A-I      3'UTR chr22:44336474(+) A-I      intronic chr22:44336646(+) A-I      intronic chr22:44325738(+) A-I      intronic chr22:44336479(+) A-I      intronic chr22:44336679(+) A-I      intronic chr22:44338634(+) A-I      intronic chr22:44339798(+) A-I      intronic chr22:44336512(+) A-I      intronic chr22:44343089(+) A-I      3'UTR chr22:44343196(+) A-I      3'UTR chr22:44343118(+) A-I      3'UTR chr22:44343029(+) A-I      3'UTR chr22:44343088(+) A-I      3'UTR chr22:44343164(+) A-I      3'UTR chr22:44342983(+) A-I      3'UTR chr22:44343062(+) A-I      3'UTR chr22:44343119(+) A-I      3'UTR chr22:44343167(+) A-I      3'UTR chr22:44336920(+) A-I      intronic chr22:44329489(+) A-I      intronic chr22:44329336(+) A-I      intronic chr22:44336433(+) A-I      intronic chr22:44339888(+) A-I      intronic chr22:44330152(+) A-I      intronic chr22:44329493(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PNPLA3	chr22:44329489(+) A-I intron -    21960545 chr22:44329493(+) A-I intron -    21960545 chr22:44329501(+) A-I intron -    21960545 chr22:44336474(+) A-I intron -    21960545 chr22:44343118(+) A-I intron -    21960545 chr22:44343119(+) A-I intron -    21960545 chr22:44343196(+) A-I intron -    21960545

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PNPLA3	chr22:44319669-44319670(+) m6A 5'UTR       25456834 chr22:44319727-44319728(+) m6A 5'UTR       25456834 chr22:44342086-44342087(+) m6A CDS//intron       24284625 chr22:44342100-44342101(+) m6A CDS//intron       24284625 chr22:44342133-44342134(+) m6A CDS//intron       24284625//25456834 chr22:44342179-44342180(+) m6A CDS//intron       24284625//25456834 chr22:44342557-44342558(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr22:44351380-44351381(+) m6A intron       24284625//24981863 chr22:44351454-44351455(+) m6A intron       24284625//24981863 chr22:44351463-44351464(+) m6A intron       24284625//24981863 chr22:44358981-44358982(+) m6A intron       24981863 chr22:44359059-44359060(+) m6A intron       24981863 chr22:44359093-44359094(+) m6A intron       24981863 chr22:44359098-44359099(+) m6A intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PNPLA3	Cytosol HCC cell line (HepG2)     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H5
Interactor2: PNPLA3

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg