Basic Information:

  VIRBase ID:  

VHID00203731

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H5:  MIMAT0015650          UPF1:  NM_001297549     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H5	UPF1
miRBase Accession/Entrez ID	MIMAT0015650	5976
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HUPF1//NORF1//pNORF1//RENT1//smg-2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	UPF1	chr19:18949326(+) A-I      intronic chr19:18949336(+) A-I      intronic chr19:18950150(+) A-I      intronic chr19:18950163(+) A-I      intronic chr19:18952783(+) A-I      intronic chr19:18952811(+) A-I      intronic chr19:18953741(+) A-I      intronic chr19:18953868(+) A-I      intronic chr19:18954578(+) A-I      intronic chr19:18949293(+) A-I      intronic chr19:18949298(+) A-I      intronic chr19:18952825(+) A-I      intronic chr19:18953619(+) A-I      intronic chr19:18953728(+) A-I      intronic chr19:18949337(+) A-I      intronic chr19:18949346(+) A-I      intronic chr19:18950077(+) A-I      intronic chr19:18950100(+) A-I      intronic chr19:18950142(+) A-I      intronic chr19:18949320(+) A-I      intronic chr19:18949268(+) A-I      intronic chr19:18949050(+) A-I      intronic chr19:18953906(+) A-I      intronic chr19:18953648(+) A-I      intronic chr19:18950042(+) A-I      intronic chr19:18950040(+) A-I      intronic chr19:18954451(+) A-I      intronic chr19:18954808(+) A-I      intronic chr19:18950030(+) A-I      intronic chr19:18954604(+) A-I      intronic chr19:18954408(+) A-I      intronic chr19:18950112(+) A-I      intronic chr19:18949981(+) A-I      intronic chr19:18954603(+) A-I      intronic chr19:18954694(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	UPF1	chr19:18942988-18942989(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18943051-18943052(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18943067-18943068(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18943233-18943234(+) m6A CDS       24209618 chr19:18956876-18956877(+) Am CDS//exon       - chr19:18960956-18960957(+) m6A CDS//exon       24284625 chr19:18961528-18961529(+) m6A CDS//exon       24284625 chr19:18961540-18961541(+) m6A CDS//exon       24284625 chr19:18961570-18961571(+) m6A CDS//exon       24284625 chr19:18962947-18962948(+) m6A CDS//exon       24284625 chr19:18962968-18962969(+) m6A CDS//exon       24284625 chr19:18965947-18965948(+) m6A CDS//exon       24284625 chr19:18965961-18965962(+) m6A CDS//exon       24284625 chr19:18966080-18966081(+) m6A exon//intron       24284625 chr19:18966771-18966772(+) m6A CDS       24284625//22608085 chr19:18966888-18966889(+) m6A CDS       24284625//25456834//22608085 chr19:18966894-18966895(+) m6A CDS       24284625//25456834//22608085 chr19:18967034-18967035(+) m6A CDS       24284625//25456834//22608085 chr19:18970219-18970220(+) m6A exon//intron       24284625 chr19:18970226-18970227(+) m6A exon//intron       24284625 chr19:18970708-18970709(+) m6A exon//intron       22608085 chr19:18970729-18970730(+) m6A exon//intron       22608085 chr19:18971178-18971179(+) m6A CDS//exon       24284625 chr19:18971243-18971244(+) m6A CDS//exon       24284625 chr19:18971696-18971697(+) m6A CDS//exon       24284625 chr19:18972864-18972865(+) m6A CDS//exon       22575960 chr19:18976123-18976124(+) m6A CDS//exon       24284625 chr19:18976178-18976179(+) m6A CDS//exon       24284625 chr19:18976236-18976237(+) m6A CDS//exon       24284625 chr19:18976354-18976355(+) m6A exon//intron       24284625 chr19:18976392-18976393(+) m6A CDS//exon       24284625 chr19:18976417-18976418(+) m6A CDS//exon       24284625 chr19:18976436-18976437(+) m6A CDS//exon       24284625 chr19:18976446-18976447(+) m6A CDS//exon       24284625 chr19:18976907-18976908(+) m6A CDS//exon       24284625 chr19:18977429-18977430(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27773536 chr19:18977453-18977454(+) Cm 3'UTR//exon       - chr19:18977621-18977622(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18977686-18977687(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:18977709-18977710(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18977747-18977748(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18977954-18977955(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr19:18977982-18977983(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085 chr19:18977991-18977992(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085 chr19:18978145-18978146(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18978163-18978164(+) Y 3'UTR//exon       26075521 chr19:18978174-18978175(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18978242-18978243(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18978329-18978330(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18978390-18978391(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr19:18978484-18978485(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr19:18978520-18978521(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr19:18978669-18978670(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18978698-18978699(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18978737-18978738(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr19:18978945-18978946(+) m6A 3'UTR//exon       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	UPF1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Blood     - Insoluble cytoplasm K562 cells     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H5
Interactor2: UPF1

Evidence Support:

Prediction-Evidence	cRep//miRanda//RNAHybrid
Support Database	RepTar//VmiReg