Basic Information:

  VIRBase ID:  

VHID00197871

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H25:  MIMAT0014708          PTGES2:  NM_198938     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H25	PTGES2
miRBase Accession/Entrez ID	MIMAT0014708	80142
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C9orf15//GBF-1//GBF1//mPGES-2//PGES2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PTGES2	chr9:130886459(-) A-I      intronic chr9:130886642(-) A-I      intronic chr9:130888309(-) A-I      intronic chr9:130884044(-) A-I      intronic chr9:130886635(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PTGES2	chr9:130883027-130883028(-) m6A 3'UTR//exon       24284625//24981863 chr9:130883033-130883034(-) m6A 3'UTR//exon       24284625//24981863 chr9:130883109-130883110(-) m6A 3'UTR//exon       24284625 chr9:130883162-130883163(-) m6A 3'UTR//exon       24284625 chr9:130884683-130884684(-) m6A CDS//exon       27773536 chr9:130884728-130884729(-) m6A CDS//exon       27773536 chr9:130884743-130884744(-) m6A CDS//exon       27773536 chr9:130889745-130889746(-) m6A CDS//exon//intron       27773536 chr9:130889991-130889992(-) m6A CDS//exon//intron       24209618//27773536 chr9:130890459-130890460(-) m6A 5'UTR//intron       24284625 chr9:130890484-130890485(-) m6A 5'UTR//intron       24284625//24981863//22608085 chr9:130890551-130890552(-) m6A 5'UTR//exon       24284625//25456834//22608085 chr9:130890640-130890641(-) m6A 5'UTR//exon       25456834//24981863//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsv2-miR-H25	Exosome K562 cells     24460325
	PTGES2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H25
Interactor2: PTGES2

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid//Targetscan
Support Database	VmiReg