Basic Information:

  VIRBase ID:  

VHID00197824

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H25:  MIMAT0014708          PNPLA2:  NM_020376     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H25	PNPLA2
miRBase Accession/Entrez ID	MIMAT0014708	57104
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	1110001C14Rik//ATGL//FP17548//iPLA2zeta//PEDF-R//TTS-2.2//TTS2

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PNPLA2	chr11:818938-818939(+) m6A 5'UTR       24981863 chr11:818952-818953(+) m6A 5'UTR       24981863 chr11:819596-819597(+) m6A 5'UTR       24209618//25456834//24981863//27371828 chr11:819620-819621(+) m6A 5'UTR       24209618//25456834//24981863//27371828 chr11:819691-819692(+) m6A 5'UTR       24284625//24209618//24981863//27371828 chr11:819743-819744(+) m6A CDS       24284625 chr11:820933-820934(+) m6A 5'UTR//exon//intron       - chr11:821055-821056(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863//22608085 chr11:821095-821096(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863//22608085 chr11:821169-821170(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863//22608085 chr11:821191-821192(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863//22608085 chr11:821235-821236(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863//22608085 chr11:822421-822422(+) m6A 5'UTR//CDS//exon       - chr11:822448-822449(+) m6A 5'UTR//CDS//exon       - chr11:822499-822500(+) m6A 5'UTR//CDS//exon       22575960 chr11:823595-823596(+) m6A 5'UTR//exon//intron       24284625 chr11:823663-823664(+) m6A 5'UTR//exon//intron       24284625 chr11:823702-823703(+) m6A 5'UTR//CDS//exon       24284625 chr11:823756-823757(+) m6A 5'UTR//CDS//exon       24284625 chr11:823762-823763(+) m6A 5'UTR//CDS//exon       24284625 chr11:824027-824028(+) m6A 5'UTR//CDS//exon       - chr11:824345-824346(+) m6A CDS//exon       - chr11:824764-824765(+) m6A CDS//exon       24284625//22575960 chr11:824863-824864(+) m6A 3'UTR//CDS//exon       24284625 chr11:824882-824883(+) m6A 3'UTR//CDS//exon       24284625 chr11:824929-824930(+) m6A 3'UTR//CDS//exon       24284625 chr11:825112-825113(+) m6A 3'UTR//exon       24284625//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsv2-miR-H25	Exosome K562 cells     24460325
	PNPLA2	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H25
Interactor2: PNPLA2

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid//Targetscan
Support Database	VmiReg