Basic Information:

  VIRBase ID:  

VHID00197671

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H25:  MIMAT0014708          MAEA:  NR_123716     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H25	MAEA
miRBase Accession/Entrez ID	MIMAT0014708	10296
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	EMLP//EMP//GID9//HLC-10//P44EMLP//PIG5

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MAEA	chr4:1296542(+) A-I      intronic chr4:1296998(+) A-I      intronic chr4:1296999(+) A-I      intronic chr4:1297063(+) A-I      intronic chr4:1297129(+) A-I      intronic chr4:1297172(+) A-I      intronic chr4:1292769(+) A-I      intronic chr4:1287113(+) A-I      intronic chr4:1292739(+) A-I      intronic chr4:1295353(+) A-I      intronic chr4:1295396(+) A-I      intronic chr4:1295402(+) A-I      intronic chr4:1295414(+) A-I      intronic chr4:1295423(+) A-I      intronic chr4:1295375(+) A-I      intronic chr4:1307256(+) A-I      intronic chr4:1296367(+) A-I      intronic chr4:1324185(+) A-I      intronic chr4:1296372(+) A-I      intronic chr4:1296394(+) A-I      intronic chr4:1296450(+) A-I      intronic chr4:1296444(+) A-I      intronic chr4:1296475(+) A-I      intronic chr4:1296413(+) A-I      intronic chr4:1324186(+) A-I      intronic chr4:1324170(+) A-I      intronic chr4:1326433(+) A-I      intronic chr4:1296529(+) A-I      intronic chr4:1295370(+) A-I      intronic chr4:1295434(+) A-I      intronic chr4:1297109(+) A-I      intronic chr4:1307606(+) A-I      intronic chr4:1287095(+) A-I      intronic chr4:1296988(+) A-I      intronic chr4:1297122(+) A-I      intronic chr4:1295369(+) A-I      intronic chr4:1306490(+) A-I      intronic chr4:1296407(+) A-I      intronic chr4:1326245(+) A-I      intronic chr4:1307701(+) A-I      intronic chr4:1296922(+) A-I      intronic chr4:1296348(+) A-I      intronic chr4:1296997(+) A-I      intronic chr4:1287069(+) A-I      intronic chr4:1292929(+) A-I      intronic chr4:1313452(+) A-I      intronic chr4:1326304(+) A-I      intronic chr4:1295347(+) A-I      intronic chr4:1296960(+) A-I      intronic chr4:1312885(+) A-I      intronic chr4:1296530(+) A-I      intronic chr4:1287059(+) A-I      intronic chr4:1296989(+) A-I      intronic chr4:1296397(+) A-I      intronic chr4:1296965(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MAEA	chr4:1286732(+) A-G intron -    22484847 chr4:1287059(+) A-G intron -    22484847 chr4:1287095(+) A-G intron -    22484847 chr4:1287125(+) A-G intron -    22484847 chr4:1296348(+) A-G intron -    22484847 chr4:1313452(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MAEA	chr4:1291760-1291761(+) m6A CDS//intron       24284625//24981863 chr4:1291817-1291818(+) m6A CDS//intron       24284625 chr4:1293607-1293608(+) m6A exon//intron       24981863 chr4:1303717-1303718(+) m6A 5'UTR//intron       - chr4:1305785-1305786(+) m6A 3'UTR//5'UTR//CDS//exon       24284625 chr4:1305812-1305813(+) m6A 3'UTR//5'UTR//CDS//exon       24284625 chr4:1305826-1305827(+) m6A 3'UTR//5'UTR//CDS//exon       24284625 chr4:1305890-1305891(+) m6A 3'UTR//CDS//exon       24284625 chr4:1305990-1305991(+) m6A CDS//exon//intron       24284625 chr4:1306022-1306023(+) m6A 3'UTR//exon//intron       24284625 chr4:1306353-1306354(+) m6A exon//intron       24284625 chr4:1326514-1326515(+) m6A exon//intron       - chr4:1326544-1326545(+) m6A CDS//exon       24284625 chr4:1330658-1330659(+) m6A CDS//exon       24284625 chr4:1330727-1330728(+) m6A CDS//exon       24284625 chr4:1330738-1330739(+) Y CDS//exon       26075521 chr4:1330777-1330778(+) m6A CDS//exon       24284625 chr4:1330888-1330889(+) m6A exon//intron       24284625 chr4:1331420-1331421(+) m6A exon//intron       24284625 chr4:1332209-1332210(+) m6A CDS//exon//intron       24284625 chr4:1332274-1332275(+) m6A 3'UTR//CDS//exon       24284625 chr4:1332358-1332359(+) m6A 3'UTR//CDS//exon       24284625 chr4:1332906-1332907(+) m6A 3'UTR//CDS//exon       24284625 chr4:1333140-1333141(+) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr4:1333216-1333217(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr4:1333230-1333231(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr4:1333240-1333241(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr4:1333252-1333253(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr4:1333327-1333328(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr4:1333402-1333403(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr4:1333440-1333441(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr4:1333545-1333546(+) m6A 3'UTR//exon       24284625//24209618//22575960//22608085 chr4:1333678-1333679(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr4:1333789-1333790(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr4:1333797-1333798(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr4:1333817-1333818(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22608085 chr4:1333880-1333881(+) m6A 3'UTR//exon       24284625//24981863//22608085 chr4:1333893-1333894(+) m6A 3'UTR//exon       24284625//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsv2-miR-H25	Exosome K562 cells     24460325
	MAEA	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H25
Interactor2: MAEA

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid
Support Database	VmiReg