Basic Information:

  VIRBase ID:  

VHID00193853

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H23-5p:  MIMAT0014705          CTSA:  NR_133656     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H23-5p	CTSA
miRBase Accession/Entrez ID	MIMAT0014705	5476
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	GLB2//GSL//NGBE//PPCA//PPGB

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CTSA	chr20:44527292(+) A-I      3'UTR chr20:44527301(+) A-I      3'UTR chr20:44524003(+) A-I      intronic chr20:44524723(+) A-I      intronic chr20:44524306(+) A-I      intronic chr20:44527269(+) A-I      3'UTR chr20:44527273(+) A-I      3'UTR chr20:44527281(+) A-I      3'UTR chr20:44524745(+) A-I      intronic chr20:44524727(+) A-I      intronic chr20:44524681(+) A-I      intronic chr20:44524673(+) A-I      intronic chr20:44524672(+) A-I      intronic chr20:44524648(+) A-I      intronic chr20:44524638(+) A-I      intronic chr20:44524445(+) A-I      intronic chr20:44524421(+) A-I      intronic chr20:44524305(+) A-I      intronic chr20:44524204(+) A-I      intronic chr20:44524191(+) A-I      intronic chr20:44524186(+) A-I      intronic chr20:44524060(+) A-I      intronic chr20:44524024(+) A-I      intronic chr20:44524823(+) A-I      intronic chr20:44524786(+) A-I      intronic chr20:44524779(+) A-I      intronic chr20:44524775(+) A-I      intronic chr20:44524768(+) A-I      intronic chr20:44524746(+) A-I      intronic chr20:44524498(+) A-I      intronic chr20:44524740(+) A-I      intronic chr20:44524624(+) A-I      intronic chr20:44524691(+) A-I      intronic chr20:44525217(+) A-I      intronic chr20:44525189(+) A-I      intronic chr20:44524386(+) A-I      intronic chr20:44524713(+) A-I      intronic chr20:44524619(+) A-I      intronic chr20:44524635(+) A-I      intronic chr20:44524319(+) A-I      intronic chr20:44524113(+) A-I      intronic chr20:44524010(+) A-I      intronic chr20:44524579(+) A-I      intronic chr20:44524730(+) A-I      intronic chr20:44525099(+) A-I      intronic chr20:44524029(+) A-I      intronic chr20:44524093(+) A-I      intronic chr20:44524232(+) A-I      intronic chr20:44524059(+) A-I      intronic chr20:44523983(+) A-I      intronic chr20:44524226(+) A-I      intronic chr20:44524337(+) A-I      intronic chr20:44524514(+) A-I      intronic chr20:44524299(+) A-I      intronic chr20:44524755(+) A-I      intronic chr20:44525171(+) A-I      intronic chr20:44524213(+) A-I      intronic chr20:44525350(+) A-I      intronic chr20:44524407(+) A-I      intronic chr20:44524766(+) A-I      intronic chr20:44524759(+) A-I      intronic chr20:44524485(+) A-I      intronic chr20:44524413(+) A-I      intronic chr20:44524669(+) A-I      intronic chr20:44524578(+) A-I      intronic chr20:44524080(+) A-I      intronic chr20:44524149(+) A-I      intronic chr20:44525211(+) A-I      intronic chr20:44524784(+) A-I      intronic chr20:44524117(+) A-I      intronic chr20:44524424(+) A-I      intronic chr20:44524687(+) A-I      intronic chr20:44524458(+) A-I      intronic chr20:44524332(+) A-I      intronic chr20:44524046(+) A-I      intronic chr20:44524463(+) A-I      intronic chr20:44524813(+) A-I      intronic chr20:44524707(+) A-I      intronic chr20:44524650(+) A-I      intronic chr20:44524187(+) A-I      intronic chr20:44523999(+) A-I      intronic chr20:44524212(+) A-I      intronic chr20:44524294(+) A-I      intronic chr20:44524459(+) A-I      intronic chr20:44525152(+) A-I      intronic chr20:44524446(+) A-I      intronic chr20:44524359(+) A-I      intronic chr20:44524385(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CTSA	chr20:44524313(+) A-I intron -    21960545   //22327324 chr20:44524444(+) A-I intron -    21960545   //22327324 chr20:44524459(+) A-I intron -    21960545   //22327324 chr20:44524619(+) A-I intron -    21960545   //22327324 chr20:44524755(+) A-I intron -    22327324 chr20:44524759(+) A-I intron -    22327324 chr20:44524713(+) A-I intron -    21960545 chr20:44524714(+) A-I intron -    21960545 chr20:44524730(+) A-I intron -    21960545 chr20:44524740(+) A-I intron -    21960545 chr20:44523991(+) A-G intron -    22484847 chr20:44524034(+) A-G intron -    22484847 chr20:44524039(+) A-G intron -    22484847 chr20:44524063(+) A-G intron -    22484847 chr20:44524149(+) A-G intron -    22484847 chr20:44524187(+) A-G intron -    22484847 chr20:44524217(+) A-G intron -    22484847 chr20:44524299(+) A-G intron -    22484847 chr20:44524313(+) A-G intron -    22484847 chr20:44524444(+) A-G intron -    22484847 chr20:44524459(+) A-G intron -    22484847 chr20:44524614(+) A-G intron -    22484847 chr20:44524619(+) A-G intron -    22484847 chr20:44524624(+) A-G intron -    22484847 chr20:44524657(+) A-G intron -    22484847 chr20:44524663(+) A-G intron -    22484847 chr20:44524669(+) A-G intron -    22484847 chr20:44524714(+) A-G intron -    22484847 chr20:44524730(+) A-G intron -    22484847 chr20:44524754(+) A-G intron -    22484847 chr20:44524755(+) A-G intron -    22484847 chr20:44524759(+) A-G intron -    22484847 chr20:44525189(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CTSA	chr20:44518905-44518906(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr20:44518933-44518934(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr20:44519055-44519056(+) m6A 5'UTR       24284625//25456834//22608085 chr20:44519176-44519177(+) m6A 5'UTR       27773536 chr20:44519295-44519296(+) m6A 5'UTR       25456834//27773536 chr20:44519335-44519336(+) m6A 5'UTR       25456834//27773536 chr20:44519354-44519355(+) m6A 5'UTR       25456834//27773536 chr20:44519378-44519379(+) m6A 5'UTR       25456834//27773536 chr20:44519436-44519437(+) m6A 5'UTR       25456834//27773536 chr20:44519903-44519904(+) m6A 5'UTR       24981863 chr20:44519926-44519927(+) m6A 5'UTR       24981863 chr20:44520473-44520474(+) m6A exon//intron       24284625 chr20:44522645-44522646(+) m6A 3'UTR//CDS//exon       - chr20:44522664-44522665(+) m6A 3'UTR//CDS//exon       - chr20:44522923-44522924(+) m6A exon//intron       - chr20:44522942-44522943(+) m6A exon//intron       - chr20:44523472-44523473(+) m6A 3'UTR//CDS//exon       24284625//22575960 chr20:44523666-44523667(+) m6A 3'UTR//CDS//exon       24284625//22575960 chr20:44523762-44523763(+) m6A 3'UTR//CDS//exon       24284625 chr20:44526389-44526390(+) m6A 3'UTR//CDS//exon       24284625 chr20:44526683-44526684(+) m6A 3'UTR//CDS//exon       24284625//27773535 chr20:44527072-44527073(+) m6A 3'UTR//CDS//exon       24284625 chr20:44527159-44527160(+) Y 3'UTR//exon       25219674 chr20:44527198-44527199(+) m6A 3'UTR//exon       24284625 chr20:44527231-44527232(+) m6A 3'UTR//exon       24284625//27773535//22575960 chr20:44527254-44527255(+) m6A 3'UTR//exon       24284625//27773535//22575960 chr20:44527367-44527368(+) m6A 3'UTR//exon       24284625//24981863//27773535 chr20:44527384-44527385(+) m6A 3'UTR//exon       24284625//24981863//27773535 chr20:44527410-44527411(+) m6A 3'UTR//exon       24284625//24981863//27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CTSA	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H23-5p
Interactor2: CTSA

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg