Basic Information:

  VIRBase ID:  

VHID00193767

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H23-5p:  MIMAT0014705          RAB8A:  NM_005370     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H23-5p	RAB8A
miRBase Accession/Entrez ID	MIMAT0014705	4218
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	MEL//RAB8

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RAB8A	chr19:16227489(+) A-I      intronic chr19:16227486(+) A-I      intronic chr19:16227484(+) A-I      intronic chr19:16225312(+) A-I      intronic chr19:16224316(+) A-I      intronic chr19:16224942(+) A-I      intronic chr19:16225004(+) A-I      intronic chr19:16225251(+) A-I      intronic chr19:16225280(+) A-I      intronic chr19:16225304(+) A-I      intronic chr19:16225316(+) A-I      intronic chr19:16225423(+) A-I      intronic chr19:16225987(+) A-I      intronic chr19:16225991(+) A-I      intronic chr19:16226023(+) A-I      intronic chr19:16227524(+) A-I      intronic chr19:16228168(+) A-I      intronic chr19:16228201(+) A-I      intronic chr19:16224233(+) A-I      intronic chr19:16224484(+) A-I      intronic chr19:16225062(+) A-I      intronic chr19:16224958(+) A-I      intronic chr19:16224980(+) A-I      intronic chr19:16227691(+) A-I      intronic chr19:16225226(+) A-I      intronic chr19:16225273(+) A-I      intronic chr19:16227534(+) A-I      intronic chr19:16224289(+) A-I      intronic chr19:16224981(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RAB8A	chr19:16222720-16222721(+) m6A CDS//exon       24284625//24981863 chr19:16222757-16222758(+) m6A CDS//exon       24284625//24981863 chr19:16222774-16222775(+) m6A CDS//exon       24284625//24981863 chr19:16223186-16223187(+) m6A exon//intron       24284625//24981863 chr19:16223219-16223220(+) m6A exon//intron       24284625//24981863 chr19:16229055-16229056(+) m6A CDS//exon       24209618 chr19:16229084-16229085(+) m6A CDS//exon       24209618 chr19:16229088-16229089(+) Cm CDS//exon       - chr19:16232561-16232562(+) m6A CDS//exon       24209618 chr19:16232626-16232627(+) m6A exon//intron       22575960 chr19:16236334-16236335(+) m6A CDS//exon       - chr19:16236446-16236447(+) m6A exon//intron       - chr19:16236485-16236486(+) m6A exon//intron       - chr19:16236502-16236503(+) m6A exon//intron       - chr19:16236969-16236970(+) m6A exon//intron       - chr19:16236987-16236988(+) m6A exon//intron       - chr19:16237022-16237023(+) m6A exon//intron       - chr19:16237030-16237031(+) m6A exon//intron       - chr19:16237287-16237288(+) m6A exon//intron       - chr19:16237312-16237313(+) m6A exon//intron       - chr19:16237365-16237366(+) m6A exon//intron       - chr19:16237375-16237376(+) m6A exon//intron       - chr19:16238868-16238869(+) m6A CDS//exon       27773535 chr19:16240403-16240404(+) m6A CDS//exon       24209618//24981863//27773535//22608085 chr19:16243070-16243071(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085 chr19:16243117-16243118(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr19:16243561-16243562(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr19:16243589-16243590(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr19:16243648-16243649(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:16243659-16243660(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:16243697-16243698(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:16243862-16243863(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr19:16244044-16244045(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr19:16244050-16244051(+) Gm 3'UTR       - chr19:16244060-16244061(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr19:16244085-16244086(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr19:16244096-16244097(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:16244199-16244200(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:16244211-16244212(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr19:16244301-16244302(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr19:16244333-16244334(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr19:16244413-16244414(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr19:16244483-16244484(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr19:16244512-16244513(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr19:16244584-16244585(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr19:16244692-16244693(+) m6A 3'UTR       24284625//24981863 chr19:16244849-16244850(+) m6A 3'UTR       24284625 chr19:16244878-16244879(+) m6A 3'UTR       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	RAB8A	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H23-5p
Interactor2: RAB8A

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg