Basic Information:

  VIRBase ID:  

VHID00192844

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H22:  MIMAT0014704          TRIM65:  NM_001256124     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H22	TRIM65
miRBase Accession/Entrez ID	MIMAT0014704	201292
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	4732463G12Rik

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TRIM65	chr17:73885252(-) A-I      3'UTR chr17:73885195(-) A-I      3'UTR chr17:73885242(-) A-I      3'UTR chr17:73885304(-) A-I      3'UTR chr17:73885355(-) A-I      3'UTR chr17:73885364(-) A-I      3'UTR chr17:73885896(-) A-I      3'UTR chr17:73885904(-) A-I      3'UTR chr17:73886213(-) A-I      3'UTR chr17:73886239(-) A-I      3'UTR chr17:73886270(-) A-I      3'UTR chr17:73886295(-) A-I      3'UTR chr17:73885139(-) A-I      3'UTR chr17:73885381(-) A-I      3'UTR chr17:73886212(-) A-I      3'UTR chr17:73885198(-) A-I      3'UTR chr17:73886260(-) A-I      3'UTR chr17:73886196(-) A-I      3'UTR chr17:73886252(-) A-I      3'UTR chr17:73885301(-) A-I      3'UTR chr17:73885407(-) A-I      3'UTR chr17:73886201(-) A-I      3'UTR chr17:73885337(-) A-I      3'UTR chr17:73885424(-) A-I      3'UTR chr17:73885229(-) A-I      3'UTR chr17:73886006(-) A-I      3'UTR chr17:73886008(-) A-I      3'UTR chr17:73886004(-) A-I      3'UTR chr17:73886234(-) A-I      3'UTR chr17:73885912(-) A-I      3'UTR chr17:73886263(-) A-I      3'UTR chr17:73885293(-) A-I      3'UTR chr17:73885269(-) A-I      3'UTR chr17:73885988(-) A-I      3'UTR chr17:73885430(-) A-I      3'UTR chr17:73885245(-) A-I      3'UTR chr17:73886856(-) A-I      3'UTR chr17:73885939(-) A-I      3'UTR chr17:73885331(-) A-I      3'UTR chr17:73885402(-) A-I      3'UTR chr17:73886249(-) A-I      3'UTR chr17:73885233(-) A-I      3'UTR chr17:73885408(-) A-I      3'UTR chr17:73885274(-) A-I      3'UTR chr17:73885275(-) A-I      3'UTR chr17:73885190(-) A-I      3'UTR chr17:73885234(-) A-I      3'UTR chr17:73885265(-) A-I      3'UTR chr17:73886219(-) A-I      3'UTR chr17:73885369(-) A-I      3'UTR chr17:73885248(-) A-I      3'UTR chr17:73885922(-) A-I      3'UTR chr17:73885934(-) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TRIM65	chr17:73885198(-) A-I exon 3'UTR    22327324 chr17:73885939(-) A-I exon 3'UTR    21960545   //22327324 chr17:73886004(-) A-I exon 3'UTR    22327324 chr17:73886212(-) A-I exon 3'UTR    22327324 chr17:73886292(-) A-I exon 3'UTR    21960545 chr17:73885274(-) A-G exon 3'UTR    21725310 chr17:73885407(-) A-G exon 3'UTR    21725310 chr17:73885939(-) A-G exon 3'UTR    21725310   //22484847 chr17:73885198(-) A-G exon 3'UTR    22484847 chr17:73885233(-) A-G exon 3'UTR    22484847 chr17:73885265(-) A-G exon 3'UTR    22484847 chr17:73885275(-) A-G exon 3'UTR    22484847 chr17:73885293(-) A-G exon 3'UTR    22484847 chr17:73885912(-) A-G exon 3'UTR    22484847 chr17:73885934(-) A-G exon 3'UTR    22484847 chr17:73886004(-) A-G exon 3'UTR    22484847 chr17:73886212(-) A-G exon 3'UTR    22484847 chr17:73886252(-) A-G exon 3'UTR    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TRIM65	chr17:73885056-73885057(-) m6A 3'UTR//intron       27773535 chr17:73885100-73885101(-) m6A 3'UTR//intron       27773535 chr17:73885105-73885106(-) m6A 3'UTR//intron       24981863//27773535 chr17:73885164-73885165(-) m6A 3'UTR//intron       24981863//27773535 chr17:73885189-73885190(-) m6A 3'UTR//intron       24981863//27773535 chr17:73885232-73885233(-) m6A 3'UTR//intron       24981863 chr17:73885833-73885834(-) Y 3'UTR//intron       26075521 chr17:73886452-73886453(-) m6A 3'UTR//intron       24284625//25456834//24981863//27773535//27371828//22575960//22608085 chr17:73886527-73886528(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr17:73886560-73886561(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr17:73886577-73886578(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr17:73886629-73886630(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr17:73886676-73886677(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr17:73886773-73886774(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr17:73886781-73886782(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr17:73886927-73886928(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960 chr17:73887002-73887003(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr17:73887046-73887047(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr17:73887124-73887125(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr17:73887156-73887157(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr17:73887172-73887173(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr17:73887238-73887239(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr17:73887364-73887365(-) m6A 3'UTR//CDS       24284625//24981863//22575960 chr17:73887903-73887904(-) m6A CDS//intron       24284625//27773535 chr17:73888105-73888106(-) m6A CDS//intron       24284625//27773535//27371828 chr17:73888201-73888202(-) m6A CDS//intron       24284625//27371828//27773536 chr17:73888358-73888359(-) m6A CDS       24284625//27371828//27773536 chr17:73888693-73888694(-) m6A exon//intron       24284625//27371828 chr17:73888760-73888761(-) m6A exon//intron       24284625//27773536 chr17:73892696-73892697(-) m6A CDS//exon       24981863//27773536 chr17:73892896-73892897(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22608085 chr17:73892905-73892906(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22608085 chr17:73892956-73892957(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	TRIM65	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H22
Interactor2: TRIM65

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg