Basic Information:

  VIRBase ID:  

VHID00190031

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H22:  MIMAT0014704          ERLIN2:  NM_001003791     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H22	ERLIN2
miRBase Accession/Entrez ID	MIMAT0014704	11160
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C8orf2//Erlin-2//NET32//SPFH2//SPG18

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ERLIN2	chr8:37597401(+) A-I      intronic chr8:37596283(+) A-I      intronic chr8:37597463(+) A-I      intronic chr8:37597417(+) A-I      intronic chr8:37597427(+) A-I      intronic chr8:37597349(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ERLIN2	chr8:37604909(+) A-I intron -    22327324 chr8:37605049(+) A-I intron -    22327324 chr8:37605148(+) A-I intron -    22327324 chr8:37605166(+) A-I intron -    22327324 chr8:37605193(+) A-I intron -    22327324 chr8:37605227(+) A-I intron -    22327324 chr8:37605263(+) A-I intron -    22327324 chr8:37605304(+) A-I intron -    22327324 chr8:37605414(+) A-I intron -    22327324 chr8:37605436(+) A-I intron -    22327324 chr8:37597349(+) A-G intron -    22484847 chr8:37597427(+) A-G intron -    22484847 chr8:37597441(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ERLIN2	chr8:37594332-37594333(+) m6A 5'UTR//intron       24284625 chr8:37594373-37594374(+) m6A 5'UTR//intron       24284625 chr8:37594406-37594407(+) m6A 5'UTR//intron       24284625 chr8:37607357-37607358(+) m6A CDS//exon       24981863 chr8:37607650-37607651(+) m6A exon//intron       24981863 chr8:37607663-37607664(+) m6A exon//intron       24981863 chr8:37607675-37607676(+) m6A exon//intron       24981863 chr8:37607925-37607926(+) m6A CDS       24981863 chr8:37607951-37607952(+) m6A CDS       24284625//24981863//27773535 chr8:37607979-37607980(+) m6A CDS       24284625//24981863//27773535 chr8:37609205-37609206(+) m6A CDS       24284625//24209618//24981863 chr8:37611511-37611512(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr8:37611532-37611533(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr8:37611602-37611603(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr8:37611638-37611639(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr8:37611764-37611765(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr8:37611803-37611804(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr8:37611892-37611893(+) m6A 3'UTR       24284625//24981863//22608085 chr8:37612894-37612895(+) m6A 3'UTR       - chr8:37613045-37613046(+) m6A 3'UTR       - chr8:37613508-37613509(+) m6A 3'UTR       - chr8:37613530-37613531(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ERLIN2	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H22
Interactor2: ERLIN2

Evidence Support:

Prediction-Evidence	cRep//miRanda//Targetscan
Support Database	RepTar//VmiReg