Basic Information:

  VIRBase ID:  

VHID00185394

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H20:  MIMAT0014702          TMBIM6:  NM_001098576     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H20	TMBIM6
miRBase Accession/Entrez ID	MIMAT0014702	7009
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BAXI1//BI-1//TEGT

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TMBIM6	chr12:50153498(+) A-I      intronic chr12:50153502(+) A-I      intronic chr12:50153378(+) A-I      intronic chr12:50153539(+) A-I      intronic chr12:50155138(+) A-I      intronic chr12:50153423(+) A-I      intronic chr12:50154461(+) A-I      intronic chr12:50139490(+) A-I      intronic chr12:50155151(+) A-I      intronic chr12:50154437(+) A-I      intronic chr12:50154297(+) A-I      intronic chr12:50153535(+) A-I      intronic chr12:50139377(+) A-I      intronic chr12:50139388(+) A-I      intronic chr12:50153540(+) A-I      intronic chr12:50139348(+) A-I      intronic chr12:50154179(+) A-I      intronic chr12:50137154(+) A-I      intronic chr12:50153426(+) A-I      intronic chr12:50154605(+) A-I      intronic chr12:50140031(+) A-I      intronic chr12:50154277(+) A-I      intronic chr12:50139897(+) A-I      intronic chr12:50154389(+) A-I      intronic chr12:50154459(+) A-I      intronic chr12:50154213(+) A-I      intronic chr12:50154503(+) A-I      intronic chr12:50148880(+) A-I      intronic chr12:50139509(+) A-I      intronic chr12:50140864(+) A-I      intronic chr12:50139349(+) A-I      intronic chr12:50154230(+) A-I      intronic chr12:50154500(+) A-I      intronic chr12:50140830(+) A-I      intronic chr12:50154599(+) A-I      intronic chr12:50154494(+) A-I      intronic chr12:50154740(+) A-I      intronic chr12:50153515(+) A-I      intronic chr12:50153326(+) A-I      intronic chr12:50153330(+) A-I      intronic chr12:50154289(+) A-I      intronic chr12:50137257(+) A-I      intronic chr12:50154587(+) A-I      intronic chr12:50154240(+) A-I      intronic chr12:50154420(+) A-I      intronic chr12:50139352(+) A-I      intronic chr12:50154831(+) A-I      intronic chr12:50153427(+) A-I      intronic chr12:50140758(+) A-I      intronic chr12:50153491(+) A-I      intronic chr12:50148870(+) A-I      intronic chr12:50153402(+) A-I      intronic chr12:50153373(+) A-I      intronic chr12:50153748(+) A-I      intronic chr12:50154253(+) A-I      intronic chr12:50154485(+) A-I      intronic chr12:50154495(+) A-I      intronic chr12:50154560(+) A-I      intronic chr12:50153499(+) A-I      intronic chr12:50154842(+) A-I      intronic chr12:50153510(+) A-I      intronic chr12:50154051(+) A-I      intronic chr12:50154232(+) A-I      intronic chr12:50153511(+) A-I      intronic chr12:50154601(+) A-I      intronic chr12:50153467(+) A-I      intronic chr12:50154741(+) A-I      intronic chr12:50153774(+) A-I      intronic chr12:50153505(+) A-I      intronic chr12:50154175(+) A-I      intronic chr12:50154449(+) A-I      intronic chr12:50153392(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TMBIM6	chr12:50139348(+) A-G intron -    22484847 chr12:50139349(+) A-G intron -    22484847 chr12:50139352(+) A-G intron -    22484847 chr12:50139897(+) A-G intron -    22484847 chr12:50153326(+) A-G intron -    22484847 chr12:50153330(+) A-G intron -    22484847 chr12:50153774(+) A-G intron -    22484847 chr12:50154051(+) A-G intron -    22484847 chr12:50154175(+) A-G intron -    22484847 chr12:50154389(+) A-G intron -    22484847 chr12:50154420(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TMBIM6	chr12:50135404-50135405(+) m6A 5'UTR//intron       24284625//25456834//24981863//27773535 chr12:50135420-50135421(+) m6A 5'UTR//intron       24284625//25456834//24981863//27773535 chr12:50144465-50144466(+) m6A 5'UTR//intron       24284625//24981863//22575960 chr12:50146253-50146254(+) m6A 5'UTR//CDS       24284625//24981863//22575960 chr12:50146265-50146266(+) m6A 5'UTR//CDS       24284625//24981863//22575960 chr12:50146273-50146274(+) m6A 5'UTR//CDS       24284625//24981863//22575960 chr12:50146280-50146281(+) m6A CDS       24284625//24981863//22575960 chr12:50146756-50146757(+) m6A 5'UTR//CDS       24981863//22575960 chr12:50153080-50153081(+) m6A CDS//exon       27773535 chr12:50155531-50155532(+) m6A CDS//exon       27773535 chr12:50155590-50155591(+) m6A exon//intron       27773535 chr12:50155639-50155640(+) m6A exon//intron       27773535 chr12:50155897-50155898(+) m6A exon//intron       27773535 chr12:50156706-50156707(+) m6A 3'UTR//exon       27773535 chr12:50156836-50156837(+) m6A 3'UTR//exon       27773535 chr12:50156966-50156967(+) m6A 3'UTR       22575960 chr12:50157027-50157028(+) m6A 3'UTR       22575960 chr12:50157033-50157034(+) m6A 3'UTR       22575960 chr12:50157101-50157102(+) m6A 3'UTR       22575960 chr12:50157185-50157186(+) Am 3'UTR       - chr12:50157586-50157587(+) m6A 3'UTR       26404942 chr12:50157611-50157612(+) m6A 3'UTR       26404942 chr12:50157623-50157624(+) m6A 3'UTR       26404942 chr12:50157764-50157765(+) m6A 3'UTR       - chr12:50158313-50158314(+) m6A 3'UTR       27773535 chr12:50158342-50158343(+) m6A 3'UTR       27773535 chr12:50158418-50158419(+) m6A 3'UTR       27773535 chr12:50158468-50158469(+) m6A 3'UTR       27773535 chr12:50158522-50158523(+) m6A 3'UTR       26404942//27773535 chr12:50158636-50158637(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	TMBIM6	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Nucleoplasm HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H20
Interactor2: TMBIM6

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg