Basic Information:

  VIRBase ID:  

VHID00183024

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H13:  MIMAT0014700          HEMK1:  NM_001377426     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H13	HEMK1
miRBase Accession/Entrez ID	MIMAT0014700	51409
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HEMK//MPRMC//MTQ1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	HEMK1	chr3:50612775(+) A-I      intronic chr3:50614038(+) A-I      intronic chr3:50614050(+) A-I      intronic chr3:50612664(+) A-I      intronic chr3:50614061(+) A-I      intronic chr3:50612689(+) A-I      intronic chr3:50612717(+) A-I      intronic chr3:50612733(+) A-I      intronic chr3:50614098(+) A-I      intronic chr3:50613901(+) A-I      intronic chr3:50614021(+) A-I      intronic chr3:50614075(+) A-I      intronic chr3:50613911(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	HEMK1	chr3:50612733(+) A-G intron -    22484847 chr3:50613911(+) A-G intron -    22484847 chr3:50613974(+) A-G intron -    22484847 chr3:50614098(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	HEMK1	chr3:50607060-50607061(+) m6A 5'UTR//exon//intron       - chr3:50607098-50607099(+) m6A 5'UTR//exon//intron       - chr3:50619791-50619792(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:50619971-50619972(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr3:50620069-50620070(+) m6A 3'UTR       24284625//24981863//22608085 chr3:50620084-50620085(+) m6A 3'UTR       24284625//24981863//22608085 chr3:50620119-50620120(+) m6A 3'UTR       24981863//22608085 chr3:50620383-50620384(+) m6A 3'UTR       24284625//24981863//22608085 chr3:50620389-50620390(+) m6A 3'UTR       24284625//24981863//22608085 chr3:50620450-50620451(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr3:50620549-50620550(+) m6A 3'UTR       22608085 chr3:50620716-50620717(+) m6A 3'UTR       - chr3:50620766-50620767(+) m6A 3'UTR       - chr3:50621412-50621413(+) m6A 3'UTR       24284625 chr3:50621483-50621484(+) m6A 3'UTR       22608085 chr3:50621541-50621542(+) m6A 3'UTR       22608085 chr3:50621584-50621585(+) m6A 3'UTR       24284625//22608085 chr3:50621673-50621674(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:50621712-50621713(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:50621725-50621726(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:50621737-50621738(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:50621775-50621776(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:50621814-50621815(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:50621855-50621856(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:50621915-50621916(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr3:50622050-50622051(+) m6A 3'UTR       24981863//22608085 chr3:50622121-50622122(+) m6A 3'UTR       24284625//24981863//22608085 chr3:50622148-50622149(+) m6A 3'UTR       24284625//24981863//22608085 chr3:50622190-50622191(+) m6A 3'UTR       24284625//24981863//22608085 chr3:50622396-50622397(+) m6A 3'UTR       - chr3:50622415-50622416(+) m6A 3'UTR       - chr3:50622421-50622422(+) m6A 3'UTR       - chr3:50622487-50622488(+) m6A 3'UTR       - chr3:50622495-50622496(+) m6A 3'UTR       - chr3:50622538-50622539(+) m6A 3'UTR       - chr3:50622591-50622592(+) m6A 3'UTR       - chr3:50622607-50622608(+) m6A 3'UTR       - chr3:50622616-50622617(+) m6A 3'UTR       - chr3:50622622-50622623(+) m6A 3'UTR       - chr3:50622669-50622670(+) m6A 3'UTR       - chr3:50622879-50622880(+) m6A 3'UTR       - chr3:50622928-50622929(+) m6A 3'UTR       - chr3:50622934-50622935(+) m6A 3'UTR       - chr3:50622960-50622961(+) m6A 3'UTR       - chr3:50622969-50622970(+) m6A 3'UTR       - chr3:50623052-50623053(+) m6A 3'UTR       - chr3:50623094-50623095(+) m6A 3'UTR       - chr3:50623107-50623108(+) m6A 3'UTR       - chr3:50623208-50623209(+) m6A 3'UTR       - chr3:50625442-50625443(+) m6A 3'UTR       - chr3:50625460-50625461(+) m6A 3'UTR       - chr3:50626085-50626086(+) m6A 3'UTR       - chr3:50626091-50626092(+) m6A 3'UTR       - chr3:50633346-50633347(+) m6A 3'UTR       - chr3:50633370-50633371(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	HEMK1	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H13
Interactor2: HEMK1

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg