Basic Information:

  VIRBase ID:  

VHID00178207

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H11-5p:  MIMAT0014697          NPHP4:  NM_015102     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H11-5p	NPHP4
miRBase Accession/Entrez ID	MIMAT0014697	261734
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	POC10//SLSN4

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NPHP4	chr1:5984934(-) A-I      intronic chr1:5973125(-) A-I      intronic chr1:5982651(-) A-I      intronic chr1:6039762(-) A-I      intronic chr1:5984935(-) A-I      intronic chr1:5984962(-) A-I      intronic chr1:5984975(-) A-I      intronic chr1:5984983(-) A-I      intronic chr1:6033226(-) A-I      intronic chr1:6039765(-) A-I      intronic chr1:6044482(-) A-I      intronic chr1:6044593(-) A-I      intronic chr1:5983050(-) A-I      intronic chr1:6039752(-) A-I      intronic chr1:6050176(-) A-I      intronic chr1:6033519(-) A-I      intronic chr1:5983001(-) A-I      intronic chr1:5983006(-) A-I      intronic chr1:6023912(-) A-I      intronic chr1:6025192(-) A-I      intronic chr1:6030556(-) A-I      intronic chr1:6033564(-) A-I      intronic chr1:5980347(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NPHP4	chr1:5983006(-) A-G intron -    22484847 chr1:5983050(-) A-G intron -    22484847 chr1:6025192(-) A-G intron -    22484847 chr1:6039752(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NPHP4	chr1:5922882-5922883(-) m6A 3'UTR//exon       27773535 chr1:5922894-5922895(-) m6A 3'UTR//exon       27773535 chr1:5922959-5922960(-) m6A 3'UTR//exon       27773535 chr1:5923094-5923095(-) m6A 3'UTR//exon       - chr1:5923176-5923177(-) m6A 3'UTR//exon       24284625 chr1:5923367-5923368(-) m6A 3'UTR//CDS//exon       24284625//27773535//27371828//27773536 chr1:5923449-5923450(-) m6A 3'UTR//CDS//exon       27773535//27371828//27773536 chr1:5923507-5923508(-) m6A exon//intron       27773535//27371828//27773536 chr1:5923545-5923546(-) m6A exon//intron       27773535 chr1:5934645-5934646(-) m6A 3'UTR//CDS//exon       24284625 chr1:5934687-5934688(-) m6A 3'UTR//CDS//exon       24284625 chr1:5934705-5934706(-) m6A 3'UTR//CDS//exon       24284625 chr1:5934987-5934988(-) m6A 3'UTR//CDS//exon       27773536 chr1:5935125-5935126(-) m6A 3'UTR//CDS//exon       24284625//27371828//27773536 chr1:5936038-5936039(-) m6A 3'UTR//intron       27371828//27773536 chr1:5939489-5939490(-) m6A 3'UTR//intron       - chr1:5939529-5939530(-) m6A 3'UTR//intron       - chr1:5939555-5939556(-) m6A 3'UTR//intron       27773535 chr1:5939568-5939569(-) m6A CDS//intron       27773535 chr1:5939574-5939575(-) m6A CDS//intron       27773535 chr1:5941809-5941810(-) m6A exon//intron       25456834 chr1:5941847-5941848(-) m6A exon//intron       25456834//27371828 chr1:5941891-5941892(-) m6A exon//intron       25456834//27371828 chr1:5941905-5941906(-) m6A exon//intron       25456834//27371828 chr1:5941917-5941918(-) m6A exon//intron       25456834//27371828 chr1:5947001-5947002(-) m6A 3'UTR//intron       25456834 chr1:5947026-5947027(-) m6A 3'UTR//intron       25456834 chr1:5964826-5964827(-) m6A 3'UTR//CDS//exon       - chr1:5964841-5964842(-) m6A 3'UTR//CDS//exon       - chr1:5964852-5964853(-) m6A 3'UTR//CDS//exon       - chr1:5965434-5965435(-) m6A 3'UTR//CDS//exon       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	NPHP4	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Insoluble cytoplasm K562 cells     - Membrane HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H11-5p
Interactor2: NPHP4

Evidence Support:

Prediction-Evidence	miRanda//PITA
Support Database	VmiReg