Basic Information:

  VIRBase ID:  

VHID00177507

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H10:  MIMAT0014353          PDE12:  NM_001322177     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H10	PDE12
miRBase Accession/Entrez ID	MIMAT0014353	201626
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	2'-PDE//2-PDE

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PDE12	chr3:57544801(+) A-I      intronic chr3:57546192(+) A-I      3'UTR chr3:57546182(+) A-I      3'UTR chr3:57546153(+) A-I      3'UTR chr3:57546152(+) A-I      3'UTR chr3:57544357(+) A-I      intronic chr3:57544271(+) A-I      intronic chr3:57544889(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PDE12	chr3:57544357(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PDE12	chr3:57542193-57542194(+) m6A CDS       24284625 chr3:57542243-57542244(+) m6A CDS       24284625 chr3:57542290-57542291(+) m6A CDS       24284625 chr3:57542603-57542604(+) m6A CDS       24284625//22575960 chr3:57542651-57542652(+) m6A CDS       24284625//22575960//22608085 chr3:57542781-57542782(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr3:57542787-57542788(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr3:57543019-57543020(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr3:57543033-57543034(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr3:57543103-57543104(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr3:57543119-57543120(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr3:57543344-57543345(+) m6A CDS       24284625//24981863//26404942//22608085 chr3:57543356-57543357(+) m6A CDS       24284625//24981863//26404942//22608085 chr3:57545061-57545062(+) m6A CDS       24284625//24981863//22608085 chr3:57545147-57545148(+) m6A 3'UTR//intron       24284625//22608085 chr3:57545207-57545208(+) m6A 3'UTR//intron       24284625//22608085 chr3:57545244-57545245(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr3:57545337-57545338(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085 chr3:57545387-57545388(+) m6A 3'UTR//CDS       24284625//24981863//26404942//22608085 chr3:57545459-57545460(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//22608085 chr3:57545538-57545539(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085 chr3:57545619-57545620(+) m6A 3'UTR//CDS       24284625//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsv2-miR-H10	Exosome K562 cells     24460325
	PDE12	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Colon cancer cells     24393600 Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H10
Interactor2: PDE12

Evidence Support:

Prediction-Evidence	cRep//miRanda//Targetscan
Support Database	RepTar//VmiReg