Basic Information:

  VIRBase ID:  

VHID00177495

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H10:  MIMAT0014353          KLHDC8B:  NM_173546     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H10	KLHDC8B
miRBase Accession/Entrez ID	MIMAT0014353	200942
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CHL

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	KLHDC8B	chr3:49209084-49209085(+) m6A 5'UTR//exon       24284625//25456834//24981863 chr3:49210087-49210088(+) m6A 5'UTR//exon       24284625//24981863 chr3:49210171-49210172(+) m6A 5'UTR//exon       24284625 chr3:49210197-49210198(+) m6A 5'UTR//exon       24284625 chr3:49210330-49210331(+) m6A CDS//exon//intron       24284625//25456834//24981863//22608085 chr3:49210341-49210342(+) m6A CDS//exon//intron       24284625//25456834//24981863//22608085 chr3:49210352-49210353(+) m6A CDS//exon//intron       24284625//25456834//24981863//22608085 chr3:49210359-49210360(+) m6A CDS//exon//intron       24284625//25456834//24981863//22608085 chr3:49211652-49211653(+) m6A exon//intron       - chr3:49213311-49213312(+) m6A 3'UTR//exon       24284625//25456834 chr3:49213363-49213364(+) m6A 3'UTR//exon       24284625//25456834 chr3:49213412-49213413(+) m6A 3'UTR//exon       24284625 chr3:49213693-49213694(+) m6A 3'UTR//exon       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsv2-miR-H10	Exosome K562 cells     24460325
	KLHDC8B	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H10
Interactor2: KLHDC8B

Evidence Support:

Prediction-Evidence	cRep//RNAHybrid
Support Database	RepTar//VmiReg