Basic Information:

  VIRBase ID:  

VHID00174586

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H10:  MIMAT0014353          MAZ:  NR_074080     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H10	MAZ
miRBase Accession/Entrez ID	MIMAT0014353	4150
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	Pur-1//PUR1//SAF-1//SAF-2//SAF-3//ZF87//Zif87//ZNF801

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MAZ	chr16:29818962(+) A-I      NonSyn:Lys->Glu chr16:29818935(+) A-I      NonSyn:Lys->Glu chr16:29818936(+) A-I      NonSyn:Lys->Arg chr16:29818939(+) A-I      NonSyn:Asn->Ser chr16:29818951(+) A-I      NonSyn:Glu->Gly chr16:29818963(+) A-I      NonSyn:Lys->Arg

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MAZ	chr16:29818080-29818081(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr16:29818107-29818108(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr16:29818140-29818141(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr16:29818356-29818357(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960 chr16:29818473-29818474(+) m6A CDS//intron       24209618//22575960 chr16:29818652-29818653(+) m1A CDS//intron       26863196//26863410 chr16:29818655-29818656(+) m6A CDS//intron       24284625//24209618//22575960 chr16:29818938-29818939(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773536//22575960//22608085 chr16:29818989-29818990(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr16:29819064-29819065(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr16:29819577-29819578(+) m6A 5'UTR//CDS//intron       22575960 chr16:29820005-29820006(+) m6A 3'UTR//CDS//exon//intron       22575960 chr16:29820207-29820208(+) m6A 3'UTR//intron       - chr16:29820219-29820220(+) m6A 3'UTR//intron       - chr16:29820229-29820230(+) m6A 3'UTR//intron       - chr16:29820902-29820903(+) m6A CDS//intron       24284625//24209618//22575960 chr16:29820967-29820968(+) m6A CDS//intron       24284625//24209618//22575960 chr16:29820997-29820998(+) m6A CDS//intron       24284625//24209618//22575960 chr16:29821068-29821069(+) m6A 3'UTR//intron       24284625//24209618 chr16:29821748-29821749(+) m6A 3'UTR//exon//intron       26404942//27371828//22575960 chr16:29821764-29821765(+) m6A 3'UTR//exon//intron       27371828//22575960 chr16:29821797-29821798(+) m6A 3'UTR//exon//intron       27371828//22575960 chr16:29821820-29821821(+) m6A 3'UTR//exon//intron       27371828//22575960 chr16:29821884-29821885(+) m6A 3'UTR//exon//intron       22575960 chr16:29822139-29822140(+) m6A 3'UTR//exon//intron       25456834//24981863//26404942//27773535//27371828//22575960 chr16:29822185-29822186(+) Cm 3'UTR//exon//intron       - chr16:29822373-29822374(+) m1A 3'UTR//CDS//exon       26863410 chr16:29822452-29822453(+) m6A 3'UTR//CDS       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsv2-miR-H10	Exosome K562 cells     24460325
	MAZ	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H10
Interactor2: MAZ

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg