Basic Information:

  VIRBase ID:  

VHID00167975

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H7-5p:  MIMAT0014351          ORMDL3:  NM_001320802     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H7-5p	ORMDL3
miRBase Accession/Entrez ID	MIMAT0014351	94103
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ORMDL3	chr17:38078771(-) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ORMDL3	chr17:38078771(-) A-I exon 3'UTR    21960545

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ORMDL3	chr17:38077396-38077397(-) m6A 3'UTR//exon       27773535 chr17:38077530-38077531(-) m6A 3'UTR//exon       27773535 chr17:38077888-38077889(-) m6A 3'UTR//intron       27773535 chr17:38078016-38078017(-) m6A 3'UTR       24981863//28052920//27773535 chr17:38078027-38078028(-) m6A 3'UTR       24981863//28052920//27773535 chr17:38078054-38078055(-) m6A 3'UTR       24209618//24981863//28052920//27773535 chr17:38078087-38078088(-) m6A 3'UTR       24209618//24981863//28052920//27773535 chr17:38078466-38078467(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085 chr17:38078499-38078500(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr17:38078505-38078506(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr17:38078549-38078550(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr17:38078707-38078708(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr17:38078728-38078729(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085 chr17:38079463-38079464(-) m6A CDS       27773535 chr17:38079470-38079471(-) m6A CDS       27773535 chr17:38079482-38079483(-) m6A CDS       27773535 chr17:38080308-38080309(-) m6A CDS//intron       27773535 chr17:38080403-38080404(-) m6A CDS       27773535 chr17:38081426-38081427(-) m6A 5'UTR//intron       - chr17:38081445-38081446(-) m6A 5'UTR//intron       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsv2-miR-H7-5p	Exosome K562 cells     24460325
	ORMDL3	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H7-5p
Interactor2: ORMDL3

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg