Detail Information

Basic Information:


  VIRBase ID:  

VHID00161555

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H2:           ST20:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsv2-miR-H2 ST20
miRBase
Accession/Entrez ID		 MIMAT0010205 400410
Organism Human alphaherpesvirus 2 (HSV2) Homo sapiens
Category miRNA lncRNA
Alias - HCCS-1

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ST20
chr15:80210586(-) A-I      intronic
chr15:80210613(-) A-I      intronic
chr15:80210544(-) A-I      intronic
chr15:80210548(-) A-I      intronic
chr15:80210555(-) A-I      intronic
chr15:80210542(-) A-I      intronic
chr15:80210601(-) A-I      intronic
chr15:80210532(-) A-I      intronic
chr15:80210584(-) A-I      intronic
chr15:80210581(-) A-I      intronic
chr15:80210530(-) A-I      intronic
chr15:80210571(-) A-I      intronic
chr15:80210538(-) A-I      intronic
chr15:80197079(-) A-I      intronic
chr15:80214089(-) A-I      intronic
chr15:80194363(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ST20
chr15:80191267-80191268(-) m6A 3'UTR       24981863//27773535//22608085
chr15:80191331-80191332(-) m6A CDS       24284625//24981863//27773535//22608085
chr15:80191348-80191349(-) m6A CDS       24284625//24981863//27773535//22608085
chr15:80200123-80200124(-) m6A 5'UTR//intron       25456834
chr15:80207564-80207565(-) m6A 5'UTR//intron       25456834//24981863//22608085
chr15:80215800-80215801(-) m6A 5'UTR       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr15:80215970-80215971(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22608085
chr15:80215985-80215986(-) m6A 5'UTR       24284625//25456834//24981863//27371828//27773536//22608085
chr15:80216031-80216032(-) m6A 5'UTR       24284625//25456834//24981863//27371828//27773536//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate ST20
Chromatin K562 cells     -
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug ST20
6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide       9956222
Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-       9952773
1,2-Ethanediamine, N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-, monohydrochloride       9926054
Tivozanib       9911830
Zibotentan       9910224
5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide       9903786
PI-103       9884685
Osi-930       9868037
5Z-7-Oxozeaenol       9863776
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide       9826528
9H-Purine, 6-(ethylthio)-9-beta-D-ribofuranosyl-(8CI)(9CI)       95846
6-Benzylthioinosine       95263
Tiotixene       941651
Benzethonium chloride       8478
3-Hydroxy-4-(phenylazo)-2-naphthoic acid       80753
(E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one       78243717
3-Amino-7-(dimethylamino)-5-phenylphenazinium chloride       75442
5-Methyl-1,10-phenanthroline       72791
N-(3-Methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine       704473
(S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide       6918848
Belinostat       6918638
2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide       6918454
Daporinad       6914657
N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide       6852167
3-Hydroxy-3'-nitro-2-naphthanilide       67277
AICA ribonucleotide       65110
Tanespimycin       6505803
Ispinesib mesylate       6450816
Axitinib       6450551
2-Pyridinecarboxaldehyde, 2-quinolinylhydrazone       6436860
Phylanthoside       6436218
4-(N-Hydroxyacetamido)stilbene       6433723
Gemcitabine       60750
Phyllanthastatin 1       5477587
Mito-tempol       54613387
Olivomycin Transformation       54610760
Indanthren Corinth RK       5351878
Rubremetinium chloride       5351504
N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide       53340664
Vorinostat       5311
5-Quinoxalin-6-ylmethylene-thiazolidine-2,4-dione       5289247
Isotretinoin       5282379
Bis(2-hydroxy-1-naphthyl) disulfide       521106
Alsterpaullone       5005498
Dichloroplatinum; 2-(4-methoxyphenyl)ethanamine       498558
Tubastatin A       49850262
Alectinib       49806720
2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide       46943432
3-(4-(4-(2-(3-((Dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea       46885626
N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide       46191454
N-(2,2,2-Trifluoroethyl)-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzenesulfonamide       447912
Okadaic acid       446512
1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine       44551660
Refametinib       44182295
Ouabain       439501
7,13-Dihydroxy-6,14,26-trimethylspiro[2,5,11,17,24-pentaoxapentacyclo[23.2.1.03,9.04,6.09,26]octacosa-19,21-diene-27,2'-oxirane]-12,18,23-trione       433350
6,15-Dihydroxy-18-(1-hydroxyethyl)-5,14,26-trimethylspiro[2,10,13,17,24-pentaoxapentacyclo[23.2.1.03,8.08,26.012,14]octacosa-4,19,21-triene-27,2'-oxirane]-11,23-dione       430232
Foretinib       42642645
Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide       42640
Mercury, chloro-2-naphthalenyl-       425433
Janus Red B       407803
3beta-Pregna-5,20-diene-beta-D-xylopyranoside       404631
7-Epi-3,4-bis-nor-dolastatin 11       396354
2-Chloro-3-(3-(N-morpholino)propylamino)-naphthazarine       379081
Etoposide       36462
1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)-       362170
5-Fluorouracil       3385
Tamoxifen       2733526
[5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol       25262965
2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide       25257557
Ruxolitinib       25126798
Navitoclax       24978538
Tert-Butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate       24951314
Quizartinib       24889392
Vismodegib       24776445
4-(6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide       24772860
Cudc-101       24756910
(2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide       24200489
Olaparib       23725625
Lenalidomide       216326
8-Amino-5-methyl-6-phenylphenanthridin-5-ium bromide       21144180
Gsk-690693       16725726
Mercury, (acetyloxy)(pentamethylphenyl)-       16683786
Homidium bromide       14710
Astrazon Orange R       135747272
(Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide       135659062
Osi-027       135398516
Lestaurtinib       126565
Berberine chloride       12456
Dactolisib       11977753
Veliparib       11960529
N-[3-[[5-Bromo-4-[[2-(1H-imidazol-5-YL)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide       11754511
Trametinib       11707110
Idelalisib       11625818
5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine       11617559
Benzamide, 4-((1R)-1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, hydrochloride (1:1)       11507964
Linifanib       11485656
N-(6-Fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide       11373846
8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one       11327430
Pararosaniline hydrochloride       11292
Amuvatinib       11282283
(S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide       11152667
Setoglaucine       107404
Dequalinium chloride       10649
7-Ethyl-10-hydroxycamptothecin       104842
VX-702       10341154
Selumetinib       10127622
N-(3-{[5-Iodo-4-({3-[(Thiophen-2-Ylcarbonyl)amino]propyl}amino)pyrimidin-2-Yl]amino}phenyl)pyrrolidine-1-Carboxamide       10077147
Masitinib       10074640
25-Dihydrosaframycin A       100180
;1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1...       -
5,6-ethylenediquino[3,2-b       -
;9-benzyl-7-benzyloxy-2-benzyl-1-methyl-9H-carbolinium b...       -
Basic Fuchsin       -
benzo[b]naphtho[2,3-d]furan-6,11-dione, 4-chloro-3-hydroxy       -
Bleomycin (50 uM)       -
Cisplatin       -
Genentech Cpd 10       -
gramicidin       -
g-tpp       -
indoline, 5-chloro-1,3,3-trimethyl-2-methylene- (8ci)       -
JW-7-24-1       -
KIN001-244       -
KIN001-260       -
KIN001-270       -
naphtho[2,1-b]quinolizinium, 5-chloro-7-methyl- perchlorate       -
N-methyl-N-(4-(3-(pyrrolidin-1-yl)propoxy)benzyl)-4-(2,6...       -
NPK76-II-72-1       -
Nutlin-3a (-)       -
pararosaniline pamoate       -
phosphonium, triphenylpropenyl-, bromide, (e)- (8ci)       -
QL-X-138       -
QL-XI-92       -
SB52334       -
THZ-2-102-1       -
TL-1-85       -
TL-2-105       -
tp38-279       -
Tyrothricin       -
VNLG/124       -
WZ3105       -
XMD13-2       -
XMD14-99       -
XMD15-27       -

Interaction Network (The top 100 interactions):


Interactor1: hsv2-miR-H2
Interactor2: ST20

Evidence Support:


Prediction-Evidence miRanda//RNAHybrid
Support Database VmiReg

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