Basic Information:

  VIRBase ID:  

VHID00161318

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H4-3p:  MIMAT0010204          LRRC27:  NM_001143758     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H4-3p	LRRC27
miRBase Accession/Entrez ID	MIMAT0010204	80313
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	LRRC27	chr10:134152331(+) A-I      intronic chr10:134152475(+) A-I      intronic chr10:134179292(+) A-I      intronic chr10:134152434(+) A-I      intronic chr10:134151777(+) A-I      intronic chr10:134152300(+) A-I      intronic chr10:134156704(+) A-I      intronic chr10:134152388(+) A-I      intronic chr10:134152344(+) A-I      intronic chr10:134156597(+) A-I      intronic chr10:134152314(+) A-I      intronic chr10:134152488(+) A-I      intronic chr10:134151677(+) A-I      intronic chr10:134152394(+) A-I      intronic chr10:134154644(+) A-I      intronic chr10:134152353(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	LRRC27	chr10:134191458(+) A-G intron -    21725310 chr10:134152353(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	LRRC27	chr10:134161536-134161537(+) m6A CDS//exon       24284625//25456834//24981863//22608085 chr10:134161553-134161554(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr10:134161589-134161590(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr10:134161649-134161650(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr10:134161659-134161660(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr10:134161676-134161677(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr10:134161688-134161689(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr10:134161820-134161821(+) m6A CDS//exon       24209618//25456834//24981863 chr10:134161833-134161834(+) m6A CDS//exon       24209618//25456834//24981863 chr10:134161848-134161849(+) m6A CDS//exon       - chr10:134162484-134162485(+) m6A CDS//exon//intron       - chr10:134164900-134164901(+) m6A exon//intron       - chr10:134165185-134165186(+) m6A CDS//exon       25456834 chr10:134166885-134166886(+) m6A 3'UTR//intron       - chr10:134178963-134178964(+) m6A CDS//exon       24981863 chr10:134188621-134188622(+) m6A CDS//exon       24981863 chr10:134188654-134188655(+) m6A CDS//exon       24981863 chr10:134188760-134188761(+) m6A 3'UTR//exon       24981863 chr10:134188780-134188781(+) m6A 3'UTR//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	LRRC27	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H4-3p
Interactor2: LRRC27

Evidence Support:

Prediction-Evidence	miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg