Basic Information:

  VIRBase ID:  

VHID00160496

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H4-5p:  MIMAT0010203          APLF:  NM_173545     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H4-5p	APLF
miRBase Accession/Entrez ID	MIMAT0010203	200558
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	APFL//C2orf13//PALF//Xip1//ZCCHH1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	APLF	chr2:68701901(+) A-I      intronic chr2:68726794(+) A-I      intronic chr2:68752968(+) A-I      intronic chr2:68726949(+) A-I      intronic chr2:68752348(+) A-I      intronic chr2:68702009(+) A-I      intronic chr2:68707633(+) A-I      intronic chr2:68701959(+) A-I      intronic chr2:68711667(+) A-I      intronic chr2:68752349(+) A-I      intronic chr2:68711774(+) A-I      intronic chr2:68704559(+) A-I      intronic chr2:68704563(+) A-I      intronic chr2:68703495(+) A-I      intronic chr2:68701930(+) A-I      intronic chr2:68752956(+) A-I      intronic chr2:68703408(+) A-I      intronic chr2:68703362(+) A-I      intronic chr2:68703462(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	APLF	chr2:68724865(+) A-G intron -    22484847 chr2:68724913(+) A-G intron -    22484847 chr2:68703362(+) A-G intron -    22484847 chr2:68703408(+) A-G intron -    22484847 chr2:68703488(+) A-G intron -    22484847 chr2:68703495(+) A-G intron -    22484847 chr2:68704559(+) A-G intron -    22484847 chr2:68704563(+) A-G intron -    22484847 chr2:68707633(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	APLF	chr2:68765063-68765064(+) m6A 3'UTR//CDS//exon       22608085 chr2:68765079-68765080(+) m6A 3'UTR//CDS//exon       24981863//22608085 chr2:68765098-68765099(+) m6A 3'UTR//CDS//exon       24981863//22608085 chr2:68765116-68765117(+) m6A 3'UTR//CDS//exon       24981863//22608085 chr2:68765138-68765139(+) m6A 3'UTR//CDS//exon       24981863//22608085 chr2:68805041-68805042(+) m6A 3'UTR//CDS//exon       27773535 chr2:68805075-68805076(+) m6A 3'UTR//CDS//exon       27773535 chr2:68870881-68870882(+) m6A intron       25456834 chr2:68870943-68870944(+) m6A intron       25456834 chr2:68870949-68870950(+) m6A intron       25456834 chr2:68872839-68872840(+) m6A exon       25456834//24981863 chr2:68872901-68872902(+) m6A exon       25456834//24981863 chr2:68872959-68872960(+) m6A CDS//exon       25456834 chr2:68873191-68873192(+) m6A CDS//exon       25456834//24981863 chr2:68873228-68873229(+) m6A CDS//exon       25456834//24981863 chr2:68873314-68873315(+) m6A CDS//exon       25456834//24981863 chr2:68882643-68882644(+) m6A CDS//exon       25456834//24981863 chr2:68882649-68882650(+) m6A CDS//exon       25456834//24981863 chr2:68882657-68882658(+) m6A CDS//exon       25456834//24981863 chr2:68882688-68882689(+) m6A CDS//exon       25456834//24981863 chr2:68882698-68882699(+) m6A CDS//exon       25456834//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	APLF	Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H4-5p
Interactor2: APLF

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg