Basic Information:

  VIRBase ID:  

VHID00158213

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H4-5p:  MIMAT0010203          ASAH1:  NM_001363743     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H4-5p	ASAH1
miRBase Accession/Entrez ID	MIMAT0010203	427
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	AC//ACDase//ASAH//PHP//PHP32//SMAPME

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ASAH1	chr8:17928011(-) A-I      intronic chr8:17927566(-) A-I      intronic chr8:17927744(-) A-I      intronic chr8:17927726(-) A-I      intronic chr8:17927797(-) A-I      intronic chr8:17927769(-) A-I      intronic chr8:17928534(-) A-I      intronic chr8:17927755(-) A-I      intronic chr8:17928554(-) A-I      intronic chr8:17928020(-) A-I      intronic chr8:17928669(-) A-I      intronic chr8:17928514(-) A-I      intronic chr8:17928472(-) A-I      intronic chr8:17928710(-) A-I      intronic chr8:17928616(-) A-I      intronic chr8:17928544(-) A-I      intronic chr8:17928482(-) A-I      intronic chr8:17928487(-) A-I      intronic chr8:17920494(-) A-I      intronic chr8:17928629(-) A-I      intronic chr8:17928545(-) A-I      intronic chr8:17928549(-) A-I      intronic chr8:17928702(-) A-I      intronic chr8:17926528(-) A-I      intronic chr8:17928630(-) A-I      intronic chr8:17928524(-) A-I      intronic chr8:17928664(-) A-I      intronic chr8:17928495(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ASAH1	chr8:17927327(-) A-I exon CDS    21960545 chr8:17920995(-) C-A intron -    22484847 chr8:17928482(-) A-G intron -    22484847 chr8:17928495(-) A-G intron -    22484847 chr8:17928524(-) A-G intron -    22484847 chr8:17928544(-) A-G intron -    22484847 chr8:17928545(-) A-G intron -    22484847 chr8:17928549(-) A-G intron -    22484847 chr8:17928616(-) A-G intron -    22484847 chr8:17928629(-) A-G intron -    22484847 chr8:17928630(-) A-G intron -    22484847 chr8:17928664(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ASAH1	chr8:17914499-17914500(-) m6A 3'UTR       26404942 chr8:17914663-17914664(-) m6A 3'UTR       24981863//22608085 chr8:17914670-17914671(-) m6A 3'UTR       24981863//22608085 chr8:17914741-17914742(-) m6A 3'UTR       24981863//22608085 chr8:17914751-17914752(-) m6A 3'UTR       24981863//22608085 chr8:17914816-17914817(-) m6A 3'UTR       24981863 chr8:17914945-17914946(-) m6A 3'UTR       24981863 chr8:17914951-17914952(-) m6A 3'UTR       24284625//24981863//26404942 chr8:17914978-17914979(-) m6A 3'UTR       24284625//24981863//26404942 chr8:17914999-17915000(-) m6A 3'UTR       24284625//24981863//26404942 chr8:17915007-17915008(-) m6A 3'UTR       24284625//24981863//26404942 chr8:17915052-17915053(-) Tm CDS       - chr8:17916915-17916916(-) m6A CDS       22575960 chr8:17916935-17916936(-) m6A CDS       22575960 chr8:17924391-17924392(-) m6A exon//intron       27773535 chr8:17924400-17924401(-) m6A exon//intron       27773535 chr8:17924405-17924406(-) m6A exon//intron       27773535 chr8:17924421-17924422(-) m6A exon//intron       27773535 chr8:17924465-17924466(-) m6A exon//intron       27773535 chr8:17924539-17924540(-) Am exon//intron       - chr8:17933700-17933701(-) m6A exon//intron       27371828 chr8:17933720-17933721(-) m6A exon//intron       27371828 chr8:17933745-17933746(-) m6A exon//intron       27371828 chr8:17942160-17942161(-) m6A exon//intron       25456834 chr8:17942305-17942306(-) m6A CDS//exon       24284625//25456834//24981863//22608085 chr8:17942322-17942323(-) m6A 5'UTR//exon       24284625//25456834//24981863//22608085 chr8:17942474-17942475(-) m6A 5'UTR       25456834//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ASAH1	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleus HeLa-S3 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H4-5p
Interactor2: ASAH1

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg