Basic Information:

  VIRBase ID:  

VHID00158175

  Virus:  

Human alphaherpesvirus 2 (HSV2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv2-miR-H4-5p:  MIMAT0010203          ACVR2B:  NM_001106     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv2-miR-H4-5p	ACVR2B
miRBase Accession/Entrez ID	MIMAT0010203	93
Organism	Human alphaherpesvirus 2 (HSV2)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ActR-IIB//ACTRIIB//HTX4

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ACVR2B	chr3:38504502(+) A-I      intronic chr3:38506734(+) A-I      intronic chr3:38506743(+) A-I      intronic chr3:38509580(+) A-I      intronic chr3:38509606(+) A-I      intronic chr3:38509632(+) A-I      intronic chr3:38509633(+) A-I      intronic chr3:38528823(+) A-I      3'UTR chr3:38509433(+) A-I      intronic chr3:38506821(+) A-I      intronic chr3:38508689(+) A-I      intronic chr3:38506306(+) A-I      intronic chr3:38509051(+) A-I      intronic chr3:38508684(+) A-I      intronic chr3:38509128(+) A-I      intronic chr3:38509218(+) A-I      intronic chr3:38509094(+) A-I      intronic chr3:38508780(+) A-I      intronic chr3:38509168(+) A-I      intronic chr3:38509509(+) A-I      intronic chr3:38509132(+) A-I      intronic chr3:38509499(+) A-I      intronic chr3:38509623(+) A-I      intronic chr3:38509146(+) A-I      intronic chr3:38508869(+) A-I      intronic chr3:38508690(+) A-I      intronic chr3:38506796(+) A-I      intronic chr3:38506293(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ACVR2B	chr3:38508246(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ACVR2B	chr3:38495418-38495419(+) m6A 5'UTR       24981863 chr3:38495472-38495473(+) m6A 5'UTR       24981863 chr3:38495698-38495699(+) m6A 5'UTR       25456834 chr3:38524044-38524045(+) m6A CDS//exon       24284625 chr3:38524668-38524669(+) m6A CDS//exon       24284625//22608085 chr3:38524755-38524756(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr3:38524794-38524795(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr3:38524830-38524831(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085 chr3:38524848-38524849(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085 chr3:38524909-38524910(+) m6A 3'UTR       25456834//24981863//22608085 chr3:38524917-38524918(+) m6A 3'UTR       25456834//24981863//22608085 chr3:38525049-38525050(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr3:38525056-38525057(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr3:38525097-38525098(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr3:38525198-38525199(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:38525219-38525220(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:38525233-38525234(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:38525248-38525249(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr3:38525258-38525259(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr3:38525272-38525273(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr3:38525370-38525371(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr3:38525424-38525425(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:38525445-38525446(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:38525489-38525490(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:38525504-38525505(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr3:38525577-38525578(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr3:38531188-38531189(+) m6A 3'UTR       - chr3:38531227-38531228(+) m6A 3'UTR       - chr3:38534519-38534520(+) Y 3'UTR       26075521

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ACVR2B	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsv2-miR-H4-5p
Interactor2: ACVR2B

Evidence Support:

Prediction-Evidence	cRep//miRanda
Support Database	RepTar//VmiReg