Basic Information:

  VIRBase ID:  

VHID00151119

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H6-5p:  MIMAT0015281          EFHD2:  NM_024329     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H6-5p	EFHD2
miRBase Accession/Entrez ID	MIMAT0015281	79180
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	SWS1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	EFHD2	chr1:15748861(+) A-I      intronic chr1:15748848(+) A-I      intronic chr1:15749131(+) A-I      intronic chr1:15749210(+) A-I      intronic chr1:15749156(+) A-I      intronic chr1:15748839(+) A-I      intronic chr1:15749170(+) A-I      intronic chr1:15749289(+) A-I      intronic chr1:15748718(+) A-I      intronic chr1:15742004(+) A-I      intronic chr1:15751942(+) A-I      intronic chr1:15740335(+) A-I      intronic chr1:15751927(+) A-I      intronic chr1:15749236(+) A-I      intronic chr1:15748658(+) A-I      intronic chr1:15748728(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	EFHD2	chr1:15742211(+) T-C intron -    22484847 chr1:15748658(+) A-G intron -    22484847 chr1:15748718(+) A-G intron -    22484847 chr1:15749236(+) A-G intron -    22484847 chr1:15749289(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	EFHD2	chr1:15736536-15736537(+) m6A CDS       24284625//24209618//27371828//22575960 chr1:15736621-15736622(+) m6A CDS       24209618//22575960 chr1:15736657-15736658(+) m6A CDS       24209618//22575960 chr1:15736753-15736754(+) m6A CDS       22575960 chr1:15752411-15752412(+) m6A CDS       22575960 chr1:15752426-15752427(+) m6A CDS       22575960 chr1:15752442-15752443(+) m6A CDS       24209618//22575960 chr1:15752461-15752462(+) m6A CDS       24209618//22575960 chr1:15752485-15752486(+) m6A CDS       24209618//22575960 chr1:15753691-15753692(+) m6A CDS       24209618//22575960 chr1:15754397-15754398(+) m6A CDS//intron       24209618//22575960 chr1:15754423-15754424(+) m6A CDS//intron       24209618//22575960 chr1:15755154-15755155(+) m1A CDS       26863410 chr1:15755317-15755318(+) m6A 3'UTR       24209618//22575960 chr1:15755330-15755331(+) m6A 3'UTR       24209618//22575960 chr1:15755604-15755605(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr1:15755715-15755716(+) m6A 3'UTR       24284625//24209618//26404942 chr1:15755745-15755746(+) m6A 3'UTR       26404942 chr1:15755994-15755995(+) m6A 3'UTR       - chr1:15756022-15756023(+) m6A 3'UTR       - chr1:15756599-15756600(+) Gm 3'UTR       - chr1:15756637-15756638(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	EFHD2	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H6-5p
Interactor2: EFHD2

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg