Basic Information:

  VIRBase ID:  

VHID00150978

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H6-5p:  MIMAT0015281          PDLIM2:  NM_001368120     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H6-5p	PDLIM2
miRBase Accession/Entrez ID	MIMAT0015281	64236
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	MYSTIQUE//SLIM

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PDLIM2	chr8:22441618(+) A-I      intronic chr8:22441614(+) A-I      intronic chr8:22440153(+) A-I      intronic chr8:22441619(+) A-I      intronic chr8:22452364(+) A-I      3'UTR chr8:22453403(+) A-I      3'UTR chr8:22453429(+) A-I      3'UTR chr8:22453396(+) A-I      3'UTR chr8:22452321(+) A-I      3'UTR chr8:22452383(+) A-I      3'UTR chr8:22452394(+) A-I      3'UTR chr8:22440119(+) A-I      intronic chr8:22441201(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PDLIM2	chr8:22445966(+) A-I intron -    15342557 chr8:22449658(+) A-I intron -    15342557 chr8:22449664(+) A-I intron -    15342557 chr8:22449669(+) A-I intron -    15342557 chr8:22449674(+) A-I intron -    15342557 chr8:22449688(+) A-I intron -    15342557 chr8:22449712(+) A-I intron -    15342557 chr8:22449756(+) A-I intron -    15342557 chr8:22449778(+) A-I intron -    15342557 chr8:22449869(+) A-I intron -    15342557 chr8:22450466(+) A-I intron -    15342557   //15258596 chr8:22450526(+) A-I intron -    15342557   //15258596 chr8:22450528(+) A-I intron -    15342557   //15258596 chr8:22450570(+) A-I intron -    15342557   //15258596 chr8:22450572(+) A-I intron -    15258596 chr8:22450622(+) A-I intron -    15342557 chr8:22450657(+) A-I intron -    15342557 chr8:22450852(+) A-I intron -    15342557   //15258596 chr8:22450913(+) A-I intron -    15342557   //15258596 chr8:22450914(+) A-I intron -    15342557   //15258596 chr8:22450933(+) A-I intron -    15342557   //15258596 chr8:22450947(+) A-I intron -    15342557   //15258596 chr8:22450959(+) A-I intron -    15258596 chr8:22450969(+) A-I intron -    15342557   //15258596 chr8:22450970(+) A-I intron -    15342557 chr8:22450975(+) A-I intron -    15342557 chr8:22450983(+) A-I intron -    15342557 chr8:22450986(+) A-I intron -    15342557 chr8:22450996(+) A-I intron -    15342557   //15258596 chr8:22451002(+) A-I intron -    15342557   //15258596 chr8:22451022(+) A-I intron -    15258596 chr8:22451040(+) A-I intron -    15342557 chr8:22451045(+) A-I intron -    15342557   //15258596 chr8:22451047(+) A-I intron -    15342557   //15258596 chr8:22451080(+) A-I intron -    15342557 chr8:22450466(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PDLIM2	chr8:22451247-22451248(+) m6A 3'UTR//CDS//exon       24284625 chr8:22451319-22451320(+) m6A 3'UTR//CDS//exon       24284625 chr8:22451324-22451325(+) Am 3'UTR//CDS//exon       - chr8:22451492-22451493(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960 chr8:22451533-22451534(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960 chr8:22451576-22451577(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960 chr8:22451587-22451588(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960 chr8:22451597-22451598(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960 chr8:22451633-22451634(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960 chr8:22451694-22451695(+) Y 3'UTR//exon//intron       26075521 chr8:22451707-22451708(+) m6A 3'UTR//exon//intron       25456834//24981863//22575960 chr8:22451801-22451802(+) m6A 3'UTR//exon//intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PDLIM2	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H6-5p
Interactor2: PDLIM2

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg