Basic Information:

  VIRBase ID:  

VHID00150472

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H6-5p:  MIMAT0015281          CDCA8:  NM_018101     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H6-5p	CDCA8
miRBase Accession/Entrez ID	MIMAT0015281	55143
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BOR//BOREALIN//DasraB//MESRGP

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CDCA8	chr1:38159157(+) A-I      intronic chr1:38169345(+) A-I      intronic chr1:38159092(+) A-I      intronic chr1:38159151(+) A-I      intronic chr1:38159207(+) A-I      intronic chr1:38165372(+) A-I      intronic chr1:38165380(+) A-I      intronic chr1:38167891(+) A-I      intronic chr1:38159280(+) A-I      intronic chr1:38169881(+) A-I      intronic chr1:38169277(+) A-I      intronic chr1:38165336(+) A-I      intronic chr1:38165342(+) A-I      intronic chr1:38169845(+) A-I      intronic chr1:38167814(+) A-I      intronic chr1:38167878(+) A-I      intronic chr1:38171704(+) A-I      intronic chr1:38159245(+) A-I      intronic chr1:38169268(+) A-I      intronic chr1:38170420(+) A-I      intronic chr1:38160767(+) A-I      intronic chr1:38159081(+) A-I      intronic chr1:38159554(+) A-I      intronic chr1:38169226(+) A-I      intronic chr1:38169227(+) A-I      intronic chr1:38167777(+) A-I      intronic chr1:38159084(+) A-I      intronic chr1:38159648(+) A-I      intronic chr1:38169228(+) A-I      intronic chr1:38169693(+) A-I      intronic chr1:38159188(+) A-I      intronic chr1:38167651(+) A-I      intronic chr1:38159733(+) A-I      intronic chr1:38165246(+) A-I      intronic chr1:38167776(+) A-I      intronic chr1:38169657(+) A-I      intronic chr1:38159210(+) A-I      intronic chr1:38167842(+) A-I      intronic chr1:38169230(+) A-I      intronic chr1:38159171(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CDCA8	chr1:38159081(+) A-G intron -    22484847 chr1:38159084(+) A-G intron -    22484847 chr1:38159171(+) A-G intron -    22484847 chr1:38159188(+) A-G intron -    22484847 chr1:38159648(+) A-G intron -    22484847 chr1:38159733(+) A-G intron -    22484847 chr1:38167776(+) A-G intron -    22484847 chr1:38167777(+) A-G intron -    22484847 chr1:38167814(+) A-G intron -    22484847 chr1:38167842(+) A-G intron -    22484847 chr1:38169227(+) A-G intron -    22484847 chr1:38169228(+) A-G intron -    22484847 chr1:38169268(+) A-G intron -    22484847 chr1:38169657(+) A-G intron -    22484847 chr1:38169693(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CDCA8	chr1:38158243-38158244(+) m6A 5'UTR       24981863 chr1:38158687-38158688(+) m6A CDS       24981863 chr1:38161593-38161594(+) m6A CDS       24981863 chr1:38164601-38164602(+) m6A CDS       24981863//27773535 chr1:38164627-38164628(+) m6A CDS       24981863//27773535 chr1:38166184-38166185(+) m6A CDS       24981863//27773535//22575960 chr1:38167455-38167456(+) m6A CDS       24981863//22575960 chr1:38171122-38171123(+) m6A CDS       22575960 chr1:38172719-38172720(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr1:38174026-38174027(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:38174039-38174040(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:38174060-38174061(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr1:38174082-38174083(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:38174093-38174094(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:38174387-38174388(+) m6A 3'UTR       24284625//22575960 chr1:38174406-38174407(+) m6A 3'UTR       24284625//22575960 chr1:38174433-38174434(+) m6A 3'UTR       24284625//24981863//22575960 chr1:38174470-38174471(+) m6A 3'UTR       24284625//24981863 chr1:38174538-38174539(+) m6A 3'UTR       24284625//24981863 chr1:38174561-38174562(+) m6A 3'UTR       24981863 chr1:38174590-38174591(+) m6A 3'UTR       24981863 chr1:38175218-38175219(+) m6A 3'UTR       27773535 chr1:38175232-38175233(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CDCA8	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H6-5p
Interactor2: CDCA8

Evidence Support:

Prediction-Evidence	cRep//miRanda//RNAHybrid
Support Database	RepTar//VmiReg