Basic Information:

  VIRBase ID:  

VHID00149339

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H6-5p:  MIMAT0015281          IRF9:  NM_001385400     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H6-5p	IRF9
miRBase Accession/Entrez ID	MIMAT0015281	10379
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	IRF-9//ISGF3//ISGF3G//p48

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	IRF9	chr14:24632894(+) A-I      intronic chr14:24632896(+) A-I      intronic chr14:24632885(+) A-I      intronic chr14:24632887(+) A-I      intronic chr14:24632926(+) A-I      intronic chr14:24632897(+) A-I      intronic chr14:24632949(+) A-I      intronic chr14:24632927(+) A-I      intronic chr14:24632882(+) A-I      intronic chr14:24632891(+) A-I      intronic chr14:24631930(+) A-I      intronic chr14:24632943(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	IRF9	chr14:24635562(+) T-G intron -    21725310

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	IRF9	chr14:24630400-24630401(+) m6A 5'UTR       25456834//24981863 chr14:24630439-24630440(+) m6A 5'UTR       25456834//24981863 chr14:24630445-24630446(+) m6A 5'UTR       25456834//24981863 chr14:24630458-24630459(+) m6A 5'UTR       25456834//24981863 chr14:24630535-24630536(+) m6A 5'UTR//exon       25456834//24981863 chr14:24631385-24631386(+) m6A CDS//exon//intron       24209618//24981863 chr14:24631393-24631394(+) m6A CDS//exon//intron       24209618//24981863 chr14:24631458-24631459(+) m6A CDS//exon//intron       24209618//24981863 chr14:24631481-24631482(+) m6A CDS//exon//intron       24209618//24981863 chr14:24631498-24631499(+) m6A CDS//exon//intron       24209618 chr14:24631510-24631511(+) m6A CDS//exon//intron       24209618 chr14:24631549-24631550(+) m6A exon//intron       24209618 chr14:24632211-24632212(+) m6A 3'UTR//5'UTR//CDS//exon       24209618 chr14:24632237-24632238(+) m6A 3'UTR//5'UTR//CDS//exon       24209618

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	IRF9	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H6-5p
Interactor2: IRF9

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg