Basic Information:

  VIRBase ID:  

VHID00145572

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H5-5p:  MIMAT0015280          EDEM3:  NM_025191     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H5-5p	EDEM3
miRBase Accession/Entrez ID	MIMAT0015280	80267
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C1orf22

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	EDEM3	chr1:184711662(-) A-I      intronic chr1:184711657(-) A-I      intronic chr1:184711663(-) A-I      intronic chr1:184697979(-) A-I      intronic chr1:184711684(-) A-I      intronic chr1:184701066(-) A-I      intronic chr1:184701152(-) A-I      intronic chr1:184701161(-) A-I      intronic chr1:184701162(-) A-I      intronic chr1:184699702(-) A-I      intronic chr1:184701188(-) A-I      intronic chr1:184696347(-) A-I      intronic chr1:184701272(-) A-I      intronic chr1:184697937(-) A-I      intronic chr1:184697993(-) A-I      intronic chr1:184698023(-) A-I      intronic chr1:184699599(-) A-I      intronic chr1:184699638(-) A-I      intronic chr1:184696304(-) A-I      intronic chr1:184696248(-) A-I      intronic chr1:184701234(-) A-I      intronic chr1:184697812(-) A-I      intronic chr1:184701048(-) A-I      intronic chr1:184680484(-) A-I      intronic chr1:184698021(-) A-I      intronic chr1:184697970(-) A-I      intronic chr1:184719784(-) A-I      intronic chr1:184697882(-) A-I      intronic chr1:184682359(-) A-I      intronic chr1:184697855(-) A-I      intronic chr1:184696372(-) A-I      intronic chr1:184711681(-) A-I      intronic chr1:184697881(-) A-I      intronic chr1:184697913(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	EDEM3	chr1:184669798(-) A-I intron -    21960545 chr1:184697881(-) A-G intron -    22484847 chr1:184697970(-) A-G intron -    22484847 chr1:184701234(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	EDEM3	chr1:184660078-184660079(-) m6A 3'UTR       27773535 chr1:184660259-184660260(-) m6A 3'UTR       27773535 chr1:184663007-184663008(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr1:184663080-184663081(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr1:184663133-184663134(-) m6A 3'UTR//intron       24284625//24981863//27773535//22575960//22608085 chr1:184663151-184663152(-) m6A 3'UTR//intron       24284625//24981863//27773535//22575960//22608085 chr1:184663187-184663188(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr1:184663248-184663249(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr1:184663263-184663264(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr1:184663318-184663319(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr1:184663328-184663329(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr1:184663378-184663379(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:184663386-184663387(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:184663409-184663410(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:184663437-184663438(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:184663541-184663542(-) m6A CDS       24284625//24981863//27371828//22575960//22608085 chr1:184663583-184663584(-) m6A CDS       24284625//22608085 chr1:184723790-184723791(-) m6A 5'UTR//exon       - chr1:184723921-184723922(-) m6A 5'UTR//exon       24981863 chr1:184723943-184723944(-) m6A 5'UTR//exon       24981863 chr1:184724019-184724020(-) m6A 5'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	EDEM3	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H5-5p
Interactor2: EDEM3

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg