Basic Information:

  VIRBase ID:  

VHID00134960

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H18:  MIMAT0014696          RNASEH1:  NM_001286834     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H18	RNASEH1
miRBase Accession/Entrez ID	MIMAT0014696	246243
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	H1RNA//PEOB2//RNH1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RNASEH1	chr2:3601184(-) A-I      intronic chr2:3601201(-) A-I      intronic chr2:3603595(-) A-I      intronic chr2:3604034(-) A-I      intronic chr2:3604108(-) A-I      intronic chr2:3595180(-) A-I      intronic chr2:3601144(-) A-I      intronic chr2:3600716(-) A-I      intronic chr2:3600658(-) A-I      intronic chr2:3600655(-) A-I      intronic chr2:3595253(-) A-I      intronic chr2:3595234(-) A-I      intronic chr2:3595216(-) A-I      intronic chr2:3594931(-) A-I      intronic chr2:3594892(-) A-I      intronic chr2:3594583(-) A-I      intronic chr2:3603652(-) A-I      intronic chr2:3595247(-) A-I      intronic chr2:3594525(-) A-I      intronic chr2:3603720(-) A-I      intronic chr2:3601053(-) A-I      intronic chr2:3600726(-) A-I      intronic chr2:3603642(-) A-I      intronic chr2:3594564(-) A-I      intronic chr2:3595245(-) A-I      intronic chr2:3601117(-) A-I      intronic chr2:3594921(-) A-I      intronic chr2:3603993(-) A-I      intronic chr2:3594941(-) A-I      intronic chr2:3601185(-) A-I      intronic chr2:3594604(-) A-I      intronic chr2:3594698(-) A-I      intronic chr2:3603640(-) A-I      intronic chr2:3594605(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RNASEH1	chr2:3594630(-) A-G intron -    22484847 chr2:3595202(-) A-G intron -    22484847 chr2:3595247(-) A-G intron -    22484847 chr2:3600726(-) A-G intron -    22484847 chr2:3600824(-) A-G intron -    22484847 chr2:3601117(-) A-G intron -    22484847 chr2:3601185(-) A-G intron -    22484847 chr2:3603640(-) A-G intron -    22484847 chr2:3603642(-) A-G intron -    22484847 chr2:3603720(-) A-G intron -    22484847 chr2:3604041(-) C-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RNASEH1	chr2:3593182-3593183(-) m6A 3'UTR       24981863//27773535 chr2:3593284-3593285(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr2:3593347-3593348(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr2:3593378-3593379(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr2:3593389-3593390(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr2:3595530-3595531(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr2:3595566-3595567(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr2:3595600-3595601(-) m6A 3'UTR//CDS       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr2:3596249-3596250(-) m6A 3'UTR//CDS       24981863//27773535 chr2:3596266-3596267(-) m6A 3'UTR//CDS       24981863//27773535 chr2:3596276-3596277(-) m6A 3'UTR//CDS       24981863//27773535 chr2:3596283-3596284(-) m6A 3'UTR//CDS       24981863//27773535 chr2:3596293-3596294(-) m6A 3'UTR//CDS       24981863//27773535 chr2:3596666-3596667(-) m6A 3'UTR//CDS       27773535 chr2:3596670-3596671(-) m6A 3'UTR//CDS       24981863//27773535 chr2:3596686-3596687(-) m6A 3'UTR//CDS       24981863//27773535 chr2:3597728-3597729(-) m6A exon//intron       27773535 chr2:3598058-3598059(-) m6A 3'UTR//CDS//exon       26404942 chr2:3599750-3599751(-) m6A 3'UTR//CDS//exon       26404942 chr2:3599821-3599822(-) m6A 3'UTR//CDS//exon       26404942 chr2:3605741-3605742(-) m6A CDS       27773536 chr2:3605969-3605970(-) m6A 5'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	RNASEH1	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane K562 cells     - Nucleus HeLa-S3 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H18
Interactor2: RNASEH1

Evidence Support:

Prediction-Evidence	miRanda//PITA//RNAHybrid//Targetscan
Support Database	VmiReg