Basic Information:

  VIRBase ID:  

VHID00131774

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H17:  MIMAT0014695          COPS7B:  NM_022730     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H17	COPS7B
miRBase Accession/Entrez ID	MIMAT0014695	64708
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CSN7B//SGN7b

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	COPS7B	chr2:232657055(+) A-I      intronic chr2:232669775(+) A-I      intronic chr2:232671159(+) A-I      intronic chr2:232671147(+) A-I      intronic chr2:232671182(+) A-I      intronic chr2:232669794(+) A-I      intronic chr2:232669802(+) A-I      intronic chr2:232670559(+) A-I      intronic chr2:232657016(+) A-I      intronic chr2:232657051(+) A-I      intronic chr2:232669770(+) A-I      intronic chr2:232670510(+) A-I      intronic chr2:232671183(+) A-I      intronic chr2:232657134(+) A-I      intronic chr2:232671226(+) A-I      intronic chr2:232669788(+) A-I      intronic chr2:232670452(+) A-I      intronic chr2:232671132(+) A-I      intronic chr2:232659517(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	COPS7B	chr2:232659517(+) A-G intron -    22484847 chr2:232666340(+) C-T intron -    22484847 chr2:232669770(+) A-G intron -    22484847 chr2:232669802(+) A-G intron -    22484847 chr2:232670307(+) A-G intron -    22484847 chr2:232671133(+) A-G intron -    22484847 chr2:232671156(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	COPS7B	chr2:232646418-232646419(+) m6A 5'UTR//exon       24981863 chr2:232646454-232646455(+) m6A 5'UTR//exon       24981863 chr2:232646490-232646491(+) m6A 5'UTR//exon       24981863 chr2:232646497-232646498(+) m6A 5'UTR//exon       24981863 chr2:232646510-232646511(+) m6A 5'UTR//exon       24981863 chr2:232646571-232646572(+) m6A 5'UTR//CDS//exon       25456834//24981863 chr2:232646577-232646578(+) m6A 5'UTR//CDS//exon       25456834//24981863 chr2:232651141-232651142(+) m6A 5'UTR//intron       25456834//24981863 chr2:232651227-232651228(+) m6A 5'UTR//exon//intron       24209618//25456834//24981863//22608085 chr2:232651244-232651245(+) m6A 5'UTR//exon//intron       24209618//25456834//24981863//22608085 chr2:232653291-232653292(+) m6A 5'UTR//CDS//exon//intron       24209618//25456834//24981863//22608085 chr2:232653297-232653298(+) m6A 5'UTR//CDS//exon//intron       24209618//25456834//24981863//22608085 chr2:232656403-232656404(+) m6A exon//intron       - chr2:232656422-232656423(+) m6A exon//intron       - chr2:232656482-232656483(+) m6A 3'UTR//CDS//exon//intron       - chr2:232656499-232656500(+) m6A 3'UTR//CDS//exon//intron       - chr2:232656544-232656545(+) m6A exon//intron       - chr2:232661004-232661005(+) m6A 3'UTR//CDS//exon       - chr2:232663639-232663640(+) m6A 3'UTR//CDS//exon       - chr2:232663650-232663651(+) m6A 3'UTR//CDS//exon       - chr2:232672214-232672215(+) m6A 3'UTR//CDS//exon       - chr2:232672406-232672407(+) m6A 3'UTR//exon//intron       24284625 chr2:232672453-232672454(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085 chr2:232672508-232672509(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085 chr2:232672558-232672559(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085 chr2:232672588-232672589(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085 chr2:232672598-232672599(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085 chr2:232672778-232672779(+) Y 3'UTR//exon//intron       26075521 chr2:232673149-232673150(+) m6A 3'UTR//CDS//exon       24284625 chr2:232673245-232673246(+) m6A 3'UTR//CDS//exon       24284625//25456834 chr2:232673332-232673333(+) m6A 3'UTR//exon       24284625//25456834//24981863 chr2:232673342-232673343(+) m6A 3'UTR//exon       25456834//24981863 chr2:232673350-232673351(+) m6A 3'UTR//exon       25456834//24981863 chr2:232673356-232673357(+) m6A 3'UTR//exon       25456834//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	COPS7B	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H17
Interactor2: COPS7B

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg