Basic Information:

  VIRBase ID:  

VHID00126026

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H16:  MIMAT0014694          NKIRAS2:  NM_001144927     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H16	NKIRAS2
miRBase Accession/Entrez ID	MIMAT0014694	28511
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	kappaB-Ras2//KBRAS2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NKIRAS2	chr17:40176638(+) A-I      3'UTR chr17:40176654(+) A-I      3'UTR chr17:40176635(+) A-I      3'UTR chr17:40176630(+) A-I      3'UTR chr17:40176662(+) A-I      3'UTR chr17:40176671(+) A-I      3'UTR chr17:40176680(+) A-I      3'UTR chr17:40172945(+) A-I      intronic chr17:40175151(+) A-I      NonSyn:Arg->Gly chr17:40176571(+) A-I      3'UTR chr17:40175150(+) A-I      Syn:Leu->Leu chr17:40175114(+) A-I      Syn:Pro->Pro chr17:40175052(+) A-I      NonSyn:Thr->Ala chr17:40175090(+) A-I      Syn:Thr->Thr

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NKIRAS2	chr17:40175052(+) A-I intron -    15258596 chr17:40175090(+) A-I intron -    15258596 chr17:40175114(+) A-I intron -    15258596 chr17:40175150(+) A-I intron -    15258596 chr17:40175151(+) A-I intron -    15258596

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NKIRAS2	chr17:40169446-40169447(+) m6A 5'UTR//intron       24284625//25456834//24981863//27773536 chr17:40172138-40172139(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863 chr17:40172228-40172229(+) m6A 5'UTR//intron       24284625//25456834//24981863 chr17:40172556-40172557(+) m6A exon//intron       27773535 chr17:40173588-40173589(+) m6A 5'UTR//exon//intron       24209618 chr17:40173646-40173647(+) m6A CDS//exon//intron       24209618 chr17:40173677-40173678(+) m6A CDS//exon//intron       24209618 chr17:40173713-40173714(+) m6A exon//intron       24209618 chr17:40173723-40173724(+) m1A exon//intron       26863410//26863196 chr17:40174443-40174444(+) m6A 3'UTR//CDS//exon//intron       - chr17:40174466-40174467(+) m6A 3'UTR//CDS//exon//intron       - chr17:40174531-40174532(+) m6A 3'UTR//CDS//exon//intron       - chr17:40175993-40175994(+) m6A 3'UTR//exon       24981863 chr17:40176325-40176326(+) m6A 3'UTR//exon       - chr17:40176614-40176615(+) m6A 3'UTR//exon       - chr17:40176712-40176713(+) m6A 3'UTR//exon       24209618//24981863 chr17:40176781-40176782(+) m6A 3'UTR//exon       24981863 chr17:40177490-40177491(+) m6A 3'UTR//exon       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	NKIRAS2	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H16
Interactor2: NKIRAS2

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg