Basic Information:

  VIRBase ID:  

VHID00126015

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H16:  MIMAT0014694          TMEM97:  NM_014573     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H16	TMEM97
miRBase Accession/Entrez ID	MIMAT0014694	27346
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	MAC30//sigma2R

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TMEM97	chr17:26654244(+) A-I      3'UTR chr17:26654249(+) A-I      3'UTR chr17:26650903(+) A-I      intronic chr17:26650566(+) A-I      intronic chr17:26650806(+) A-I      intronic chr17:26654225(+) A-I      3'UTR chr17:26654121(+) A-I      3'UTR chr17:26654072(+) A-I      3'UTR chr17:26650558(+) A-I      intronic chr17:26654271(+) A-I      3'UTR chr17:26654232(+) A-I      3'UTR chr17:26654117(+) A-I      3'UTR chr17:26654113(+) A-I      3'UTR chr17:26654008(+) A-I      3'UTR chr17:26650987(+) A-I      intronic chr17:26650705(+) A-I      intronic chr17:26650965(+) A-I      intronic chr17:26654127(+) A-I      3'UTR chr17:26654137(+) A-I      3'UTR chr17:26654231(+) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TMEM97	chr17:26654232(+) A-I intron -    21960545 chr17:26654113(+) A-G intron -    22484847 chr17:26654121(+) A-G intron -    22484847 chr17:26654137(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TMEM97	chr17:26652535-26652536(+) m6A 5'UTR//CDS//intron       24284625 chr17:26652568-26652569(+) m6A 5'UTR//CDS//intron       24284625 chr17:26652829-26652830(+) m6A 3'UTR//intron       24284625//24209618//22608085 chr17:26653579-26653580(+) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr17:26653680-26653681(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr17:26653686-26653687(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr17:26653693-26653694(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr17:26653824-26653825(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr17:26653887-26653888(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr17:26653899-26653900(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr17:26653924-26653925(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr17:26653963-26653964(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr17:26653973-26653974(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr17:26654009-26654010(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr17:26654123-26654124(+) m6A 3'UTR       24209618//24981863 chr17:26654183-26654184(+) m6A 3'UTR       24209618 chr17:26654280-26654281(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr17:26654299-26654300(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr17:26654328-26654329(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22575960//22608085 chr17:26654436-26654437(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr17:26654441-26654442(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr17:26654448-26654449(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr17:26654459-26654460(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr17:26654520-26654521(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr17:26655132-26655133(+) m6A 3'UTR       27773535 chr17:26655361-26655362(+) m6A 3'UTR       27773535 chr17:26655428-26655429(+) m6A 3'UTR       27773535 chr17:26655508-26655509(+) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085 chr17:26655522-26655523(+) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	TMEM97	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H16
Interactor2: TMEM97

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg