Basic Information:

  VIRBase ID:  

VHID00122974

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H16:  MIMAT0014694          CD59:  NM_203330     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H16	CD59
miRBase Accession/Entrez ID	MIMAT0014694	966
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	16.3A5//1F5//EJ16//EJ30//EL32//G344//HRF-20//HRF20//MAC-IP//MACIF//MEM43//MIC11//MIN1//MIN2//MIN3//MIRL//MSK21//p18-20

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CD59	chr11:33723662(-) A-I      intronic chr11:33723193(-) A-I      intronic chr11:33723189(-) A-I      intronic chr11:33733146(-) A-I      intronic chr11:33733224(-) A-I      intronic chr11:33732821(-) A-I      intronic chr11:33736601(-) A-I      intronic chr11:33732754(-) A-I      intronic chr11:33732353(-) A-I      intronic chr11:33737139(-) A-I      intronic chr11:33732756(-) A-I      intronic chr11:33736599(-) A-I      intronic chr11:33736587(-) A-I      intronic chr11:33732289(-) A-I      intronic chr11:33733140(-) A-I      intronic chr11:33733225(-) A-I      intronic chr11:33737071(-) A-I      intronic chr11:33732379(-) A-I      intronic chr11:33736537(-) A-I      intronic chr11:33733136(-) A-I      intronic chr11:33723206(-) A-I      intronic chr11:33733223(-) A-I      intronic chr11:33733155(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CD59	chr11:33720019-33720020(-) m6A 3'UTR//CDS       - chr11:33730256-33730257(-) m6A 3'UTR//intron       24284625 chr11:33730474-33730475(-) Cm 3'UTR//exon//intron       - chr11:33731099-33731100(-) m6A 3'UTR//exon//intron       24284625//25456834//24981863//26404942//27773535//22575960//22608085 chr11:33731147-33731148(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:33731177-33731178(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:33731242-33731243(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:33731399-33731400(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr11:33731435-33731436(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr11:33731503-33731504(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr11:33731512-33731513(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr11:33731644-33731645(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr11:33731727-33731728(-) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr11:33731745-33731746(-) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr11:33731764-33731765(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr11:33731783-33731784(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr11:33738966-33738967(-) m6A CDS//exon       24284625//27371828//27773536//22575960 chr11:33739064-33739065(-) m6A exon//intron       24284625//27371828//27773536//22575960 chr11:33743999-33744000(-) m6A 5'UTR       24284625//25456834//24981863//22608085 chr11:33744063-33744064(-) m6A 5'UTR//intron       24284625//25456834//24981863 chr11:33752983-33752984(-) m6A 5'UTR//intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CD59	Chromatin K562 cells     - Cytosol HeLa-S3 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H16
Interactor2: CD59

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg