Basic Information:

  VIRBase ID:  

VHID00122389

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H15:  MIMAT0014693          PCSK9:  NM_174936     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H15	PCSK9
miRBase Accession/Entrez ID	MIMAT0014693	255738
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	FH3//FHCL3//HCHOLA3//LDLCQ1//NARC-1//NARC1//PC9

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PCSK9	chr1:55511463(+) A-I      intronic chr1:55516609(+) A-I      ncRNA chr1:55514012(+) A-I      intronic chr1:55516566(+) A-I      intronic chr1:55516542(+) A-I      intronic chr1:55514003(+) A-I      intronic chr1:55513999(+) A-I      intronic chr1:55513955(+) A-I      intronic chr1:55513934(+) A-I      intronic chr1:55516590(+) A-I      intronic chr1:55516556(+) A-I      intronic chr1:55516526(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PCSK9	chr1:55505305-55505306(+) m6A 5'UTR       24284625//25456834//24981863//22575960 chr1:55505398-55505399(+) m6A 5'UTR       24284625//25456834//22575960 chr1:55505454-55505455(+) m6A 5'UTR       24284625//25456834//22575960 chr1:55505486-55505487(+) m6A 5'UTR       24284625//25456834//22575960 chr1:55505687-55505688(+) m6A CDS       24284625//22575960 chr1:55505938-55505939(+) m6A intron       24284625//25456834//22575960 chr1:55505993-55505994(+) m6A intron       24284625 chr1:55509563-55509564(+) m6A CDS       24284625//22575960 chr1:55512232-55512233(+) m6A CDS       24284625//22575960 chr1:55512265-55512266(+) m6A CDS       24284625//22575960 chr1:55516660-55516661(+) m6A exon//intron       24284625 chr1:55516701-55516702(+) m6A exon//intron       24284625 chr1:55516923-55516924(+) m6A exon//intron       25456834 chr1:55516932-55516933(+) m6A exon//intron       25456834 chr1:55517050-55517051(+) m6A exon//intron       25456834 chr1:55517983-55517984(+) m6A CDS//exon       24284625 chr1:55518066-55518067(+) m6A CDS//exon       24284625 chr1:55518080-55518081(+) m6A CDS//exon       24284625 chr1:55523034-55523035(+) m6A CDS//intron       24284625 chr1:55523054-55523055(+) m6A CDS//intron       24284625 chr1:55523063-55523064(+) m6A CDS//intron       24284625 chr1:55525296-55525297(+) m6A CDS//intron       24284625//22575960 chr1:55527074-55527075(+) m6A CDS//exon       24284625//22575960 chr1:55529068-55529069(+) m6A CDS//exon       24284625 chr1:55529098-55529099(+) m6A CDS//exon       24284625 chr1:55529129-55529130(+) m6A CDS//exon       24284625 chr1:55529433-55529434(+) m6A 3'UTR//exon       24284625//25456834//22575960 chr1:55529515-55529516(+) m6A 3'UTR//exon       24284625//25456834//24981863//22575960 chr1:55529687-55529688(+) m6A 3'UTR//exon       24284625//25456834//24981863//22575960 chr1:55529820-55529821(+) m6A 3'UTR//exon       24284625//22575960 chr1:55529940-55529941(+) m6A 3'UTR//exon       24284625//25456834//24981863//22575960 chr1:55530040-55530041(+) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//22575960 chr1:55530047-55530048(+) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//22575960 chr1:55530085-55530086(+) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//22575960 chr1:55530191-55530192(+) m6A 3'UTR//exon       24284625//25456834//24981863//22575960 chr1:55530197-55530198(+) m6A 3'UTR//exon       24284625//25456834//24981863//22575960 chr1:55530245-55530246(+) m6A 3'UTR//exon       24284625//25456834//24981863 chr1:55530366-55530367(+) m6A 3'UTR//exon       24284625//25456834 chr1:55530422-55530423(+) m6A 3'UTR//exon       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PCSK9	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H15
Interactor2: PCSK9

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg