Basic Information:

  VIRBase ID:  

VHID00120924

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H15:  MIMAT0014693          VPS4A:  NM_013245     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H15	VPS4A
miRBase Accession/Entrez ID	MIMAT0014693	27183
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	SKD1//SKD1A//SKD2//VPS4//VPS4-1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	VPS4A	chr16:69348976(+) A-I      intronic chr16:69357710(+) A-I      intronic chr16:69357722(+) A-I      intronic chr16:69357774(+) A-I      intronic chr16:69349023(+) A-I      intronic chr16:69349000(+) A-I      intronic chr16:69348978(+) A-I      intronic chr16:69346590(+) A-I      intronic chr16:69346738(+) A-I      intronic chr16:69348053(+) A-I      intronic chr16:69346668(+) A-I      intronic chr16:69351700(+) A-I      intronic chr16:69357781(+) A-I      intronic chr16:69357199(+) A-I      intronic chr16:69346945(+) A-I      intronic chr16:69351697(+) A-I      intronic chr16:69349017(+) A-I      intronic chr16:69357163(+) A-I      intronic chr16:69348961(+) A-I      intronic chr16:69357109(+) A-I      intronic chr16:69347948(+) A-I      intronic chr16:69352008(+) A-I      intronic chr16:69349027(+) A-I      intronic chr16:69351641(+) A-I      intronic chr16:69357732(+) A-I      intronic chr16:69357692(+) A-I      intronic chr16:69352061(+) A-I      intronic chr16:69357273(+) A-I      intronic chr16:69357159(+) A-I      intronic chr16:69357164(+) A-I      intronic chr16:69348975(+) A-I      intronic chr16:69357241(+) A-I      intronic chr16:69357238(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	VPS4A	chr16:69357218(+) A-I intron -    22327324 chr16:69357228(+) A-I intron -    22327324 chr16:69356695(+) A-I intron -    21960545 chr16:69347948(+) A-G intron -    22484847 chr16:69356716(+) T-C intron -    22484847 chr16:69356729(+) T-C intron -    22484847 chr16:69356786(+) T-C intron -    22484847 chr16:69356888(+) T-C intron -    22484847 chr16:69356889(+) T-C intron -    22484847 chr16:69356924(+) T-C intron -    22484847 chr16:69357218(+) T-C intron -    22484847 chr16:69357228(+) T-C intron -    22484847 chr16:69357229(+) T-C intron -    22484847 chr16:69357326(+) T-C intron -    22484847 chr16:69357353(+) T-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	VPS4A	chr16:69345260-69345261(+) m6A 5'UTR       24209618 chr16:69345335-69345336(+) m6A 5'UTR       24209618 chr16:69345363-69345364(+) m6A 5'UTR       24209618 chr16:69345400-69345401(+) m6A 5'UTR       24209618 chr16:69349947-69349948(+) m6A CDS       24209618//22575960 chr16:69349959-69349960(+) m6A CDS       24209618//22575960 chr16:69350187-69350188(+) m6A CDS       24209618//24981863//27773535//22575960 chr16:69350230-69350231(+) m6A CDS       24209618//24981863//27773535//27371828//22575960 chr16:69350256-69350257(+) m6A CDS       24209618//24981863//27773535//27371828//22575960 chr16:69352594-69352595(+) m6A CDS       24209618//24981863//27773535//22575960 chr16:69352603-69352604(+) m6A CDS       24209618//24981863//27773535//22575960 chr16:69354054-69354055(+) m6A CDS//exon       - chr16:69354613-69354614(+) m6A CDS//exon       27371828//27773536 chr16:69354635-69354636(+) m6A CDS//exon       27371828//27773536 chr16:69355054-69355055(+) m6A CDS//exon       27773535 chr16:69355615-69355616(+) m6A exon//intron       27773535 chr16:69355628-69355629(+) m6A exon//intron       27773535 chr16:69355650-69355651(+) m6A exon//intron       24981863//27773535 chr16:69355760-69355761(+) m6A exon//intron       27773535 chr16:69355796-69355797(+) m6A exon//intron       27773535 chr16:69356191-69356192(+) m6A exon//intron       24284625 chr16:69356253-69356254(+) m6A exon//intron       24284625 chr16:69356312-69356313(+) m6A exon//intron       24284625 chr16:69356361-69356362(+) m6A exon//intron       24284625 chr16:69356384-69356385(+) m6A exon//intron       24284625 chr16:69356396-69356397(+) m6A exon//intron       24284625 chr16:69356532-69356533(+) m6A CDS//exon       24284625 chr16:69356574-69356575(+) m6A CDS//exon       24284625 chr16:69356578-69356579(+) m6A CDS//exon       - chr16:69358114-69358115(+) m6A CDS//exon       24284625//24981863 chr16:69358192-69358193(+) m6A CDS//exon       24284625//25456834//24981863 chr16:69358290-69358291(+) m6A 3'UTR//exon       24284625//25456834//24981863 chr16:69358386-69358387(+) m6A 3'UTR//exon       24284625//24981863 chr16:69358415-69358416(+) m6A 3'UTR//exon       24284625//24981863 chr16:69358622-69358623(+) m6A 3'UTR//exon       27773535 chr16:69358727-69358728(+) m6A 3'UTR//exon       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	VPS4A	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H15
Interactor2: VPS4A

Evidence Support:

Prediction-Evidence	cRep//miRanda//RNAHybrid
Support Database	RepTar//VmiReg