Basic Information:

  VIRBase ID:  

VHID00117066

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H14-3p:  MIMAT0014692          MAN2B2:  NM_015274     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H14-3p	MAN2B2
miRBase Accession/Entrez ID	MIMAT0014692	23324
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MAN2B2	chr4:6591188(+) A-I      intronic chr4:6591202(+) A-I      intronic chr4:6602975(+) A-I      intronic chr4:6617793(+) A-I      intronic chr4:6617657(+) A-I      intronic chr4:6617648(+) A-I      intronic chr4:6617634(+) A-I      intronic chr4:6601213(+) A-I      intronic chr4:6601211(+) A-I      intronic chr4:6601210(+) A-I      intronic chr4:6601033(+) A-I      intronic chr4:6601030(+) A-I      intronic chr4:6600954(+) A-I      intronic chr4:6600950(+) A-I      intronic chr4:6591719(+) A-I      intronic chr4:6603133(+) A-I      intronic chr4:6602976(+) A-I      intronic chr4:6602999(+) A-I      intronic chr4:6624270(+) A-I      3'UTR chr4:6624848(+) A-I      3'UTR chr4:6624269(+) A-I      3'UTR chr4:6624397(+) A-I      3'UTR chr4:6624872(+) A-I      3'UTR chr4:6624378(+) A-I      3'UTR chr4:6624235(+) A-I      3'UTR chr4:6624324(+) A-I      3'UTR chr4:6589683(+) A-I      intronic chr4:6591173(+) A-I      intronic chr4:6590308(+) A-I      intronic chr4:6600863(+) A-I      intronic chr4:6590984(+) A-I      intronic chr4:6601095(+) A-I      intronic chr4:6589621(+) A-I      intronic chr4:6592056(+) A-I      intronic chr4:6591714(+) A-I      intronic chr4:6617751(+) A-I      intronic chr4:6591574(+) A-I      intronic chr4:6624360(+) A-I      3'UTR chr4:6624277(+) A-I      3'UTR chr4:6625058(+) A-I      3'UTR chr4:6624905(+) A-I      3'UTR chr4:6624960(+) A-I      3'UTR chr4:6624305(+) A-I      3'UTR chr4:6624266(+) A-I      3'UTR chr4:6625022(+) A-I      3'UTR chr4:6624896(+) A-I      3'UTR chr4:6624970(+) A-I      3'UTR chr4:6624346(+) A-I      3'UTR chr4:6624826(+) A-I      3'UTR chr4:6624934(+) A-I      3'UTR chr4:6624881(+) A-I      3'UTR chr4:6591101(+) A-I      intronic chr4:6591133(+) A-I      intronic chr4:6590990(+) A-I      intronic chr4:6592621(+) A-I      intronic chr4:6600847(+) A-I      intronic chr4:6591048(+) A-I      intronic chr4:6590256(+) A-I      intronic chr4:6590985(+) A-I      intronic chr4:6601080(+) A-I      intronic chr4:6591026(+) A-I      intronic chr4:6591733(+) A-I      intronic chr4:6617720(+) A-I      intronic chr4:6617672(+) A-I      intronic chr4:6592819(+) A-I      intronic chr4:6604491(+) A-I      intronic chr4:6591068(+) A-I      intronic chr4:6591085(+) A-I      intronic chr4:6591032(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MAN2B2	chr4:6619165(+) A-I exon CDS    15342557 chr4:6609380(+) T-G intron -    22484847 chr4:6589621(+) A-G intron -    22484847 chr4:6589683(+) A-G intron -    22484847 chr4:6590233(+) A-G intron -    22484847 chr4:6590242(+) A-G intron -    22484847 chr4:6590256(+) A-G intron -    22484847 chr4:6590271(+) G-A intron -    22484847 chr4:6590984(+) A-G intron -    22484847 chr4:6590985(+) A-G intron -    22484847 chr4:6590990(+) A-G intron -    22484847 chr4:6591026(+) A-G intron -    22484847 chr4:6591048(+) A-G intron -    22484847 chr4:6591068(+) A-G intron -    22484847 chr4:6591085(+) A-G intron -    22484847 chr4:6591101(+) A-G intron -    22484847 chr4:6591165(+) A-G intron -    22484847 chr4:6591173(+) A-G intron -    22484847 chr4:6600847(+) A-G intron -    22484847 chr4:6600863(+) A-G intron -    22484847 chr4:6600964(+) A-G intron -    22484847 chr4:6604491(+) A-G intron -    22484847 chr4:6617427(+) T-C intron -    22484847 chr4:6617444(+) T-C intron -    22484847 chr4:6617588(+) T-C intron -    22484847 chr4:6617672(+) A-G intron -    22484847 chr4:6617720(+) A-G intron -    22484847 chr4:6617751(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MAN2B2	chr4:6606788-6606789(+) m6A CDS       - chr4:6606799-6606800(+) m6A CDS       - chr4:6606870-6606871(+) m6A CDS       - chr4:6619223-6619224(+) m6A CDS//intron       24284625 chr4:6619243-6619244(+) m6A CDS//intron       24284625 chr4:6619263-6619264(+) m6A CDS//intron       24284625 chr4:6619285-6619286(+) m6A 3'UTR//intron       24284625 chr4:6620717-6620718(+) m6A 3'UTR//intron       24284625//25456834//22608085 chr4:6620778-6620779(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr4:6620799-6620800(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr4:6620844-6620845(+) m6A 3'UTR//intron       24284625//25456834//24981863//22575960//22608085 chr4:6620888-6620889(+) m6A 3'UTR//intron       24284625//25456834//24981863//22575960//22608085 chr4:6620910-6620911(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr4:6620917-6620918(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr4:6620937-6620938(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr4:6620954-6620955(+) m6A 3'UTR//intron       24284625//25456834//22608085 chr4:6621012-6621013(+) m6A 3'UTR//intron       24284625//25456834 chr4:6621204-6621205(+) m6A 3'UTR//intron       24284625//25456834//24981863 chr4:6621214-6621215(+) m6A 3'UTR//intron       24284625//25456834//24981863 chr4:6621259-6621260(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr4:6621313-6621314(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr4:6621353-6621354(+) m6A 3'UTR//intron       24284625//25456834 chr4:6621537-6621538(+) m6A 3'UTR//intron       27773536//22608085 chr4:6621553-6621554(+) m6A 3'UTR//intron       27773536//22608085 chr4:6621612-6621613(+) m6A 3'UTR//intron       24284625//27773536 chr4:6621710-6621711(+) m6A 3'UTR//CDS       24284625//25456834//24981863//27773536 chr4:6621779-6621780(+) m6A 3'UTR//intron       24284625//25456834//24981863 chr4:6621805-6621806(+) m6A 3'UTR//intron       24284625//25456834//24981863 chr4:6621834-6621835(+) m6A 3'UTR//intron       24284625//25456834//24981863 chr4:6622549-6622550(+) m6A 3'UTR//intron       24209618 chr4:6622625-6622626(+) m6A 3'UTR//intron       24209618 chr4:6622732-6622733(+) m6A 3'UTR//intron       24284625 chr4:6622788-6622789(+) m6A 3'UTR//intron       24284625 chr4:6622830-6622831(+) m6A 3'UTR//intron       24284625//25456834 chr4:6622837-6622838(+) m6A 3'UTR//intron       24284625//25456834 chr4:6622891-6622892(+) m6A 3'UTR//intron       24284625//24981863 chr4:6623052-6623053(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr4:6623067-6623068(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr4:6623078-6623079(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr4:6623106-6623107(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr4:6623183-6623184(+) m6A 3'UTR       24284625//24209618//24981863//27773535 chr4:6623299-6623300(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr4:6623305-6623306(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr4:6623312-6623313(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr4:6623338-6623339(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr4:6623412-6623413(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr4:6623440-6623441(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr4:6623611-6623612(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr4:6623640-6623641(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr4:6623697-6623698(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr4:6623798-6623799(+) m6A 3'UTR       24981863//27773535 chr4:6623968-6623969(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr4:6624100-6624101(+) m6A 3'UTR       24981863//22608085 chr4:6624115-6624116(+) m6A 3'UTR       24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MAN2B2	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H14-3p
Interactor2: MAN2B2

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg